Berberine Inhibits the Release of Glutamate in Nerve Terminals from Rat Cerebral Cortex.

Berberine, an isoquinoline plant alkaloid, protects neurons against neurotoxicity. An excessive release of glutamate is considered to be one of the molecular mechanisms of neuronal damage in several neurological diseases. In this study, we investigated whether berberine could affect endogenous gluta...

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Autori principali: Tzu-Yu Lin, Yu-Wan Lin, Cheng-Wei Lu, Shu-Kuei Huang, Su-Jane Wang
Natura: Articolo
Lingua:English
Pubblicazione: Public Library of Science (PLoS) 2013-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC3686739?pdf=render