CT Findings in Pulmonary and Abdominal Sarcoidosis. Implications for Diagnosis and Classification
Sarcoidosis is a granulomatous disorder of unknown etiology characterized by noncaseating granulomas virtually in every organ and tissue. This finding represents the most important diagnostic clue to reach a correct definition of sarcoidosis, although the biopsy is invasive and has several risk proc...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-09-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/9/9/3028 |
| _version_ | 1797553179347386368 |
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| author | Claudio Tana Iginio Donatiello Maria Gabriella Coppola Fabrizio Ricci Marica Tina Maccarone Tiziana Ciarambino Francesco Cipollone Maria Adele Giamberardino |
| author_facet | Claudio Tana Iginio Donatiello Maria Gabriella Coppola Fabrizio Ricci Marica Tina Maccarone Tiziana Ciarambino Francesco Cipollone Maria Adele Giamberardino |
| author_sort | Claudio Tana |
| collection | DOAJ |
| description | Sarcoidosis is a granulomatous disorder of unknown etiology characterized by noncaseating granulomas virtually in every organ and tissue. This finding represents the most important diagnostic clue to reach a correct definition of sarcoidosis, although the biopsy is invasive and has several risk procedures. Several efforts are made to suspect the diagnosis of sarcoidosis by combining noninvasive elements, in particular from imaging, though these findings are often nonspecific and reflect the wide multifactorial pathogenesis. Every effort should be made to obtain a detailed radiological picture that, if associated with a suggestive clinical picture, could avoid the need of biopsy in some specific cases. In this narrative review, we aim to describe main computed tomography (CT) features of pulmonary and abdominal sarcoidosis, by reporting strengths and limits of this technique, in particular for the identification of extrapulmonary, isolated disease. |
| first_indexed | 2024-03-10T16:11:42Z |
| format | Article |
| id | doaj.art-858980a7645c4a01a434bc51d1d56ad9 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T16:11:42Z |
| publishDate | 2020-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-858980a7645c4a01a434bc51d1d56ad92023-11-20T14:24:27ZengMDPI AGJournal of Clinical Medicine2077-03832020-09-0199302810.3390/jcm9093028CT Findings in Pulmonary and Abdominal Sarcoidosis. Implications for Diagnosis and ClassificationClaudio Tana0Iginio Donatiello1Maria Gabriella Coppola2Fabrizio Ricci3Marica Tina Maccarone4Tiziana Ciarambino5Francesco Cipollone6Maria Adele Giamberardino7Geriatrics Clinic, “G. Bernabeo” Hospital, Contrada S. Liberata, 66026 Ortona (CH), ItalyInternal Medicine Unit, University Hospital of Salerno, 84131 Salerno, ItalyInternal Medicine Unit, Ospedale del Mare, 80145 Napoli, ItalyDepartment of Neuroscience, Imaging and Clinical Sciences, Institute of Advanced Biomedical Technologies, “G.d’Annunzio” University, 66100 Chieti, ItalyImaging Department, Hospital of Pescara, 65123 Pescara, ItalyInternal Medicine Unit, Marcianise Hospital, 81025 Caserta, ItalyMedical Clinic, Department of Medicine and Science of Aging, “G. D’Annunzio”, University of Chieti, 66100 Chieti, ItalyGeriatrics Clinic, Department of Medicine and Science of Aging, “G. D’Annunzio” University of Chieti, 66100 Chieti, ItalySarcoidosis is a granulomatous disorder of unknown etiology characterized by noncaseating granulomas virtually in every organ and tissue. This finding represents the most important diagnostic clue to reach a correct definition of sarcoidosis, although the biopsy is invasive and has several risk procedures. Several efforts are made to suspect the diagnosis of sarcoidosis by combining noninvasive elements, in particular from imaging, though these findings are often nonspecific and reflect the wide multifactorial pathogenesis. Every effort should be made to obtain a detailed radiological picture that, if associated with a suggestive clinical picture, could avoid the need of biopsy in some specific cases. In this narrative review, we aim to describe main computed tomography (CT) features of pulmonary and abdominal sarcoidosis, by reporting strengths and limits of this technique, in particular for the identification of extrapulmonary, isolated disease.https://www.mdpi.com/2077-0383/9/9/3028sarcoidosiscomputed tomographyimagingbiopsylungsliver |
| spellingShingle | Claudio Tana Iginio Donatiello Maria Gabriella Coppola Fabrizio Ricci Marica Tina Maccarone Tiziana Ciarambino Francesco Cipollone Maria Adele Giamberardino CT Findings in Pulmonary and Abdominal Sarcoidosis. Implications for Diagnosis and Classification Journal of Clinical Medicine sarcoidosis computed tomography imaging biopsy lungs liver |
| title | CT Findings in Pulmonary and Abdominal Sarcoidosis. Implications for Diagnosis and Classification |
| title_full | CT Findings in Pulmonary and Abdominal Sarcoidosis. Implications for Diagnosis and Classification |
| title_fullStr | CT Findings in Pulmonary and Abdominal Sarcoidosis. Implications for Diagnosis and Classification |
| title_full_unstemmed | CT Findings in Pulmonary and Abdominal Sarcoidosis. Implications for Diagnosis and Classification |
| title_short | CT Findings in Pulmonary and Abdominal Sarcoidosis. Implications for Diagnosis and Classification |
| title_sort | ct findings in pulmonary and abdominal sarcoidosis implications for diagnosis and classification |
| topic | sarcoidosis computed tomography imaging biopsy lungs liver |
| url | https://www.mdpi.com/2077-0383/9/9/3028 |
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