MYC regulates ribosome biogenesis and mitochondrial gene expression programs through its interaction with host cell factor–1
The oncoprotein transcription factor MYC is a major driver of malignancy and a highly validated but challenging target for the development of anticancer therapies. Novel strategies to inhibit MYC may come from understanding the co-factors it uses to drive pro-tumorigenic gene expression programs, pr...
主要な著者: | , , , , , , , , , , , , , |
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フォーマット: | 論文 |
言語: | English |
出版事項: |
eLife Sciences Publications Ltd
2021-01-01
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シリーズ: | eLife |
主題: | |
オンライン・アクセス: | https://elifesciences.org/articles/60191 |