MYC regulates ribosome biogenesis and mitochondrial gene expression programs through its interaction with host cell factor–1
The oncoprotein transcription factor MYC is a major driver of malignancy and a highly validated but challenging target for the development of anticancer therapies. Novel strategies to inhibit MYC may come from understanding the co-factors it uses to drive pro-tumorigenic gene expression programs, pr...
| Автори: | , , , , , , , , , , , , , |
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| Формат: | Стаття |
| Мова: | English |
| Опубліковано: |
eLife Sciences Publications Ltd
2021-01-01
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| Серія: | eLife |
| Предмети: | |
| Онлайн доступ: | https://elifesciences.org/articles/60191 |