MYC regulates ribosome biogenesis and mitochondrial gene expression programs through its interaction with host cell factor–1

MYC regulates ribosome biogenesis and mitochondrial gene expression programs through its interaction with host cell factor–1

The oncoprotein transcription factor MYC is a major driver of malignancy and a highly validated but challenging target for the development of anticancer therapies. Novel strategies to inhibit MYC may come from understanding the co-factors it uses to drive pro-tumorigenic gene expression programs, pr...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính: Tessa M Popay, Jing Wang, Clare M Adams, Gregory Caleb Howard, Simona G Codreanu, Stacy D Sherrod, John A McLean, Lance R Thomas, Shelly L Lorey, Yuichi J Machida, April M Weissmiller, Christine M Eischen, Qi Liu, William P Tansey
Định dạng: Bài viết
Ngôn ngữ:English
Được phát hành: eLife Sciences Publications Ltd 2021-01-01
Loạt:eLife
Những chủ đề:
cancer
MYC
ribosome biogenesis
Truy cập trực tuyến:https://elifesciences.org/articles/60191

Internet

https://elifesciences.org/articles/60191

Những quyển sách tương tự