P-31 Magnetic Resonance Spectroscopy. A tool for diagnostic purposes and pathophysiological insights in muscle diseases

It has been more than 15 years since 31-phosphorus magnetic resonance spectroscopy (31P-MRS) was first used in order to study human muscle diseases. Its impact on the field of neuromuscular disorders has now become considerable for pathophysiological insights and for diagnostic purposes. Recent revi...

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Main Authors: J.P. Mattei, D. Bendahan, P. Cozzone
Format: Article
Language:English
Published: PAGEPress Publications 2004-03-01
Series:Reumatismo
Online Access:https://reumatismo.org/index.php/reuma/article/view/143
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author J.P. Mattei
D. Bendahan
P. Cozzone
author_facet J.P. Mattei
D. Bendahan
P. Cozzone
author_sort J.P. Mattei
collection DOAJ
description It has been more than 15 years since 31-phosphorus magnetic resonance spectroscopy (31P-MRS) was first used in order to study human muscle diseases. Its impact on the field of neuromuscular disorders has now become considerable for pathophysiological insights and for diagnostic purposes. Recent reviews (1-3) have summarized the possibilities of the technique that permits to investigate muscle energetic metabolism non-invasively and non-destructively. In this mini-review, we will recall the information provided by a P-31 MRS spectrum when exploring a normal muscle and present the new spectral semiology that is helpful for the diagnosis of metabolic myopathies. We will also show briefly some other clinical applications of this technique.
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spelling doaj.art-858c8872eb124a40bf95955a5db322132022-12-22T02:07:35ZengPAGEPress PublicationsReumatismo0048-74492240-26832004-03-0156110.4081/reumatismo.2004.9P-31 Magnetic Resonance Spectroscopy. A tool for diagnostic purposes and pathophysiological insights in muscle diseasesJ.P. MatteiD. BendahanP. CozzoneIt has been more than 15 years since 31-phosphorus magnetic resonance spectroscopy (31P-MRS) was first used in order to study human muscle diseases. Its impact on the field of neuromuscular disorders has now become considerable for pathophysiological insights and for diagnostic purposes. Recent reviews (1-3) have summarized the possibilities of the technique that permits to investigate muscle energetic metabolism non-invasively and non-destructively. In this mini-review, we will recall the information provided by a P-31 MRS spectrum when exploring a normal muscle and present the new spectral semiology that is helpful for the diagnosis of metabolic myopathies. We will also show briefly some other clinical applications of this technique.https://reumatismo.org/index.php/reuma/article/view/143
spellingShingle J.P. Mattei
D. Bendahan
P. Cozzone
P-31 Magnetic Resonance Spectroscopy. A tool for diagnostic purposes and pathophysiological insights in muscle diseases
Reumatismo
title P-31 Magnetic Resonance Spectroscopy. A tool for diagnostic purposes and pathophysiological insights in muscle diseases
title_full P-31 Magnetic Resonance Spectroscopy. A tool for diagnostic purposes and pathophysiological insights in muscle diseases
title_fullStr P-31 Magnetic Resonance Spectroscopy. A tool for diagnostic purposes and pathophysiological insights in muscle diseases
title_full_unstemmed P-31 Magnetic Resonance Spectroscopy. A tool for diagnostic purposes and pathophysiological insights in muscle diseases
title_short P-31 Magnetic Resonance Spectroscopy. A tool for diagnostic purposes and pathophysiological insights in muscle diseases
title_sort p 31 magnetic resonance spectroscopy a tool for diagnostic purposes and pathophysiological insights in muscle diseases
url https://reumatismo.org/index.php/reuma/article/view/143
work_keys_str_mv AT jpmattei p31magneticresonancespectroscopyatoolfordiagnosticpurposesandpathophysiologicalinsightsinmusclediseases
AT dbendahan p31magneticresonancespectroscopyatoolfordiagnosticpurposesandpathophysiologicalinsightsinmusclediseases
AT pcozzone p31magneticresonancespectroscopyatoolfordiagnosticpurposesandpathophysiologicalinsightsinmusclediseases