Comparative Analysis of Chloramphenicol-Resistant <i>Enterococcus faecalis</i> Isolated from Dairy Companies in Korea
Although chloramphenicol is currently banned from use in livestock, other phenicols, such as florfenicol and thiamphenicol, have been used for the treatment of bacterial infections in domestic cattle in Korea. This study compares the characteristics of chloramphenicol-resistant <i>Enterococcus...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-07-01
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| Series: | Veterinary Sciences |
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| Online Access: | https://www.mdpi.com/2306-7381/8/8/143 |
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| author | Sung Hyun Bae Sunghyun Yoon Koeun Kim Yeong Bin Kim Young Ju Lee |
| author_facet | Sung Hyun Bae Sunghyun Yoon Koeun Kim Yeong Bin Kim Young Ju Lee |
| author_sort | Sung Hyun Bae |
| collection | DOAJ |
| description | Although chloramphenicol is currently banned from use in livestock, other phenicols, such as florfenicol and thiamphenicol, have been used for the treatment of bacterial infections in domestic cattle in Korea. This study compares the characteristics of chloramphenicol-resistant <i>Enterococcus faecalis</i> isolated from the bulk tank milk of four major dairy companies in Korea. Although the distribution of multidrug resistance patterns showed no significant differences between the four companies, 85 chloramphenicol-resistant <i>Enterococcus faecalis</i> isolates showed a significantly high number of resistances against five or six antimicrobial classes (37.6%, respectively) (<i>p</i> < 0.05). When analyzing the distribution of phenicol resistance genes, 31 (36.5%) isolates only carried the <i>catA</i> gene, and two (6.3%) isolates from company A only carried the <i>cfr</i> gene. No isolates carried the <i>catB</i> or <i>fexA</i> genes. Regarding the distribution of other resistance genes, both the <i>tetL</i> and <i>tetM</i> (45.9%), <i>ermB</i> (82.4%), and both <i>aac(6″)</i><i>-Ie-aph(2″)-la</i> and <i>ant(6′)-Ia</i> genes (30.6%) showed a high prevalence, and the <i>optrA</i> and <i>poxtA</i> genes were observed separately, each in only two (2.4%) isolates. Our results confirm that the dissemination of chloramphenicol-resistant <i>Enterococcus faecalis</i> and some antimicrobial resistance genes show significant differences between dairy companies. Therefore, our results support that each dairy company should undertake effective surveillance programs to better understand and minimize the emergence of resistance on a multidisciplinary level. |
| first_indexed | 2024-03-10T08:18:43Z |
| format | Article |
| id | doaj.art-858cb5ac375c490c9f7a3fb9602f3b0d |
| institution | Directory Open Access Journal |
| issn | 2306-7381 |
| language | English |
| last_indexed | 2024-03-10T08:18:43Z |
| publishDate | 2021-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Veterinary Sciences |
| spelling | doaj.art-858cb5ac375c490c9f7a3fb9602f3b0d2023-11-22T10:08:26ZengMDPI AGVeterinary Sciences2306-73812021-07-018814310.3390/vetsci8080143Comparative Analysis of Chloramphenicol-Resistant <i>Enterococcus faecalis</i> Isolated from Dairy Companies in KoreaSung Hyun Bae0Sunghyun Yoon1Koeun Kim2Yeong Bin Kim3Young Ju Lee4College of Veterinary Medicine and Zoonoses Research Institute, Kyungpook National University, Daegu 41566, KoreaCollege of Veterinary Medicine and Zoonoses Research Institute, Kyungpook National University, Daegu 41566, KoreaCollege of Veterinary Medicine and Zoonoses Research Institute, Kyungpook National University, Daegu 41566, KoreaCollege of Veterinary Medicine and Zoonoses Research Institute, Kyungpook National University, Daegu 41566, KoreaCollege of Veterinary Medicine and Zoonoses Research Institute, Kyungpook National University, Daegu 41566, KoreaAlthough chloramphenicol is currently banned from use in livestock, other phenicols, such as florfenicol and thiamphenicol, have been used for the treatment of bacterial infections in domestic cattle in Korea. This study compares the characteristics of chloramphenicol-resistant <i>Enterococcus faecalis</i> isolated from the bulk tank milk of four major dairy companies in Korea. Although the distribution of multidrug resistance patterns showed no significant differences between the four companies, 85 chloramphenicol-resistant <i>Enterococcus faecalis</i> isolates showed a significantly high number of resistances against five or six antimicrobial classes (37.6%, respectively) (<i>p</i> < 0.05). When analyzing the distribution of phenicol resistance genes, 31 (36.5%) isolates only carried the <i>catA</i> gene, and two (6.3%) isolates from company A only carried the <i>cfr</i> gene. No isolates carried the <i>catB</i> or <i>fexA</i> genes. Regarding the distribution of other resistance genes, both the <i>tetL</i> and <i>tetM</i> (45.9%), <i>ermB</i> (82.4%), and both <i>aac(6″)</i><i>-Ie-aph(2″)-la</i> and <i>ant(6′)-Ia</i> genes (30.6%) showed a high prevalence, and the <i>optrA</i> and <i>poxtA</i> genes were observed separately, each in only two (2.4%) isolates. Our results confirm that the dissemination of chloramphenicol-resistant <i>Enterococcus faecalis</i> and some antimicrobial resistance genes show significant differences between dairy companies. Therefore, our results support that each dairy company should undertake effective surveillance programs to better understand and minimize the emergence of resistance on a multidisciplinary level.https://www.mdpi.com/2306-7381/8/8/143<i>Enterococcus faecalis</i>chloramphenicol resistancemilkmultidrug resistance |
| spellingShingle | Sung Hyun Bae Sunghyun Yoon Koeun Kim Yeong Bin Kim Young Ju Lee Comparative Analysis of Chloramphenicol-Resistant <i>Enterococcus faecalis</i> Isolated from Dairy Companies in Korea Veterinary Sciences <i>Enterococcus faecalis</i> chloramphenicol resistance milk multidrug resistance |
| title | Comparative Analysis of Chloramphenicol-Resistant <i>Enterococcus faecalis</i> Isolated from Dairy Companies in Korea |
| title_full | Comparative Analysis of Chloramphenicol-Resistant <i>Enterococcus faecalis</i> Isolated from Dairy Companies in Korea |
| title_fullStr | Comparative Analysis of Chloramphenicol-Resistant <i>Enterococcus faecalis</i> Isolated from Dairy Companies in Korea |
| title_full_unstemmed | Comparative Analysis of Chloramphenicol-Resistant <i>Enterococcus faecalis</i> Isolated from Dairy Companies in Korea |
| title_short | Comparative Analysis of Chloramphenicol-Resistant <i>Enterococcus faecalis</i> Isolated from Dairy Companies in Korea |
| title_sort | comparative analysis of chloramphenicol resistant i enterococcus faecalis i isolated from dairy companies in korea |
| topic | <i>Enterococcus faecalis</i> chloramphenicol resistance milk multidrug resistance |
| url | https://www.mdpi.com/2306-7381/8/8/143 |
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