CURRENT PHARMACOTHERAPY FOR SYSTEMIC JUVENILE ARTHRITIS
Systemic juvenile arthritis (sJA) is one of the severest childhood somatic diseases. The relevance of the problem associated with sJA is determined by difficulties in early diagnosis, by the rapid development of disability, and by poor prognosis with a high risk for life-threatening conditions. It s...
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Format: | Article |
Language: | Russian |
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IMA PRESS LLC
2015-03-01
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Series: | Научно-практическая ревматология |
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Online Access: | https://rsp.mediar-press.net/rsp/article/view/2043 |
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author | I. P. Nikishina M. I. Kaleda |
author_facet | I. P. Nikishina M. I. Kaleda |
author_sort | I. P. Nikishina |
collection | DOAJ |
description | Systemic juvenile arthritis (sJA) is one of the severest childhood somatic diseases. The relevance of the problem associated with sJA is determined by difficulties in early diagnosis, by the rapid development of disability, and by poor prognosis with a high risk for life-threatening conditions. It still persists despite the fact that a notable advance has been made in pharmacotherapy, which could substantially change the prognosis of sJA. The use of disease-modifying anti-rheumatic drugs (DMARDs) and then the advent of biological agents (BAs) have fundamentally changed the drug regimen for the treatment of sJA. The paper considers the aspects of using different DMARDs and BAs in sJA in the context of evidence-based medicine, by analyzing the data available in the literature. |
first_indexed | 2024-04-09T22:25:18Z |
format | Article |
id | doaj.art-8596cf1db5ce4d819a5291c2675c011a |
institution | Directory Open Access Journal |
issn | 1995-4484 1995-4492 |
language | Russian |
last_indexed | 2025-03-14T08:07:03Z |
publishDate | 2015-03-01 |
publisher | IMA PRESS LLC |
record_format | Article |
series | Научно-практическая ревматология |
spelling | doaj.art-8596cf1db5ce4d819a5291c2675c011a2025-03-02T13:23:40ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922015-03-01531849310.14412/1995-4484-2015-84-931948CURRENT PHARMACOTHERAPY FOR SYSTEMIC JUVENILE ARTHRITISI. P. Nikishina0M. I. Kaleda1V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia 34A, Kashirskoe Shosse, Moscow 115522V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia 34A, Kashirskoe Shosse, Moscow 115522Systemic juvenile arthritis (sJA) is one of the severest childhood somatic diseases. The relevance of the problem associated with sJA is determined by difficulties in early diagnosis, by the rapid development of disability, and by poor prognosis with a high risk for life-threatening conditions. It still persists despite the fact that a notable advance has been made in pharmacotherapy, which could substantially change the prognosis of sJA. The use of disease-modifying anti-rheumatic drugs (DMARDs) and then the advent of biological agents (BAs) have fundamentally changed the drug regimen for the treatment of sJA. The paper considers the aspects of using different DMARDs and BAs in sJA in the context of evidence-based medicine, by analyzing the data available in the literature.https://rsp.mediar-press.net/rsp/article/view/2043systemic juvenile arthritisdisease-modifying anti-rheumatic drugsbiological agents |
spellingShingle | I. P. Nikishina M. I. Kaleda CURRENT PHARMACOTHERAPY FOR SYSTEMIC JUVENILE ARTHRITIS Научно-практическая ревматология systemic juvenile arthritis disease-modifying anti-rheumatic drugs biological agents |
title | CURRENT PHARMACOTHERAPY FOR SYSTEMIC JUVENILE ARTHRITIS |
title_full | CURRENT PHARMACOTHERAPY FOR SYSTEMIC JUVENILE ARTHRITIS |
title_fullStr | CURRENT PHARMACOTHERAPY FOR SYSTEMIC JUVENILE ARTHRITIS |
title_full_unstemmed | CURRENT PHARMACOTHERAPY FOR SYSTEMIC JUVENILE ARTHRITIS |
title_short | CURRENT PHARMACOTHERAPY FOR SYSTEMIC JUVENILE ARTHRITIS |
title_sort | current pharmacotherapy for systemic juvenile arthritis |
topic | systemic juvenile arthritis disease-modifying anti-rheumatic drugs biological agents |
url | https://rsp.mediar-press.net/rsp/article/view/2043 |
work_keys_str_mv | AT ipnikishina currentpharmacotherapyforsystemicjuvenilearthritis AT mikaleda currentpharmacotherapyforsystemicjuvenilearthritis |