CURRENT PHARMACOTHERAPY FOR SYSTEMIC JUVENILE ARTHRITIS

Systemic juvenile arthritis (sJA) is one of the severest childhood somatic diseases. The relevance of the problem associated with sJA is determined by difficulties in early diagnosis, by the rapid development of disability, and by poor prognosis with a high risk for life-threatening conditions. It s...

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Main Authors: I. P. Nikishina, M. I. Kaleda
Format: Article
Language:Russian
Published: IMA PRESS LLC 2015-03-01
Series:Научно-практическая ревматология
Subjects:
Online Access:https://rsp.mediar-press.net/rsp/article/view/2043
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author I. P. Nikishina
M. I. Kaleda
author_facet I. P. Nikishina
M. I. Kaleda
author_sort I. P. Nikishina
collection DOAJ
description Systemic juvenile arthritis (sJA) is one of the severest childhood somatic diseases. The relevance of the problem associated with sJA is determined by difficulties in early diagnosis, by the rapid development of disability, and by poor prognosis with a high risk for life-threatening conditions. It still persists despite the fact that a notable advance has been made in pharmacotherapy, which could substantially change the prognosis of sJA. The use of disease-modifying anti-rheumatic drugs (DMARDs) and then the advent of biological agents (BAs) have fundamentally changed the drug regimen for the treatment of sJA. The paper considers the aspects of using different DMARDs and BAs in sJA in the context of evidence-based medicine, by analyzing the data available in the literature.
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spelling doaj.art-8596cf1db5ce4d819a5291c2675c011a2025-03-02T13:23:40ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922015-03-01531849310.14412/1995-4484-2015-84-931948CURRENT PHARMACOTHERAPY FOR SYSTEMIC JUVENILE ARTHRITISI. P. Nikishina0M. I. Kaleda1V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia 34A, Kashirskoe Shosse, Moscow 115522V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia 34A, Kashirskoe Shosse, Moscow 115522Systemic juvenile arthritis (sJA) is one of the severest childhood somatic diseases. The relevance of the problem associated with sJA is determined by difficulties in early diagnosis, by the rapid development of disability, and by poor prognosis with a high risk for life-threatening conditions. It still persists despite the fact that a notable advance has been made in pharmacotherapy, which could substantially change the prognosis of sJA. The use of disease-modifying anti-rheumatic drugs (DMARDs) and then the advent of biological agents (BAs) have fundamentally changed the drug regimen for the treatment of sJA. The paper considers the aspects of using different DMARDs and BAs in sJA in the context of evidence-based medicine, by analyzing the data available in the literature.https://rsp.mediar-press.net/rsp/article/view/2043systemic juvenile arthritisdisease-modifying anti-rheumatic drugsbiological agents
spellingShingle I. P. Nikishina
M. I. Kaleda
CURRENT PHARMACOTHERAPY FOR SYSTEMIC JUVENILE ARTHRITIS
Научно-практическая ревматология
systemic juvenile arthritis
disease-modifying anti-rheumatic drugs
biological agents
title CURRENT PHARMACOTHERAPY FOR SYSTEMIC JUVENILE ARTHRITIS
title_full CURRENT PHARMACOTHERAPY FOR SYSTEMIC JUVENILE ARTHRITIS
title_fullStr CURRENT PHARMACOTHERAPY FOR SYSTEMIC JUVENILE ARTHRITIS
title_full_unstemmed CURRENT PHARMACOTHERAPY FOR SYSTEMIC JUVENILE ARTHRITIS
title_short CURRENT PHARMACOTHERAPY FOR SYSTEMIC JUVENILE ARTHRITIS
title_sort current pharmacotherapy for systemic juvenile arthritis
topic systemic juvenile arthritis
disease-modifying anti-rheumatic drugs
biological agents
url https://rsp.mediar-press.net/rsp/article/view/2043
work_keys_str_mv AT ipnikishina currentpharmacotherapyforsystemicjuvenilearthritis
AT mikaleda currentpharmacotherapyforsystemicjuvenilearthritis