Role of β-Lactamase Inhibitors as Potentiators in Antimicrobial Chemotherapy Targeting Gram-Negative Bacteria

Role of β-Lactamase Inhibitors as Potentiators in Antimicrobial Chemotherapy Targeting Gram-Negative Bacteria

Since the discovery of penicillin, β-lactam antibiotics have commonly been used to treat bacterial infections. Unfortunately, at the same time, pathogens can develop resistance to β-lactam antibiotics such as penicillins, cephalosporins, monobactams, and carbapenems by producing β-lactamases. Theref...

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Bibliographic Details
Main Authors: Song Zhang, Xinyu Liao, Tian Ding, Juhee Ahn
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Antibiotics
Subjects:
antibiotic resistance
β-lactamase inhibitor
β-lactam
combination therapy
Online Access:https://www.mdpi.com/2079-6382/13/3/260

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