COVID-19 related to sarcopenia: Current perspectives on etiology, clinical implications, and nutritional rehabilitation
Sarcopenia is a progressive skeletal muscle disorder characterized by reduced strength and quality. Pathophysiological mechanisms, clinical aspects, and nutritional points were related to sarcopenia in COVID-19 found in skeletal muscle during and after the disease course, which corroborated the dev...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Hospital de Clínicas de Itajubá
2023-09-01
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| Series: | Revista Ciências em Saúde |
| Subjects: | |
| Online Access: | https://portalrcs.hcitajuba.org.br/index.php/rcsfmit_zero/article/view/1436 |
| _version_ | 1797677900524158976 |
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| author | Elis Regina Muller Ramos Anderson Matheus Oliveira Haas Verdi Stephane Janaina de Moura Escobar Angelica Rocha de Freitas Melhem Mariana Abe Vicente Cavagnari Caryna Eurich Mazur Dalton Luiz Schiessel |
| author_facet | Elis Regina Muller Ramos Anderson Matheus Oliveira Haas Verdi Stephane Janaina de Moura Escobar Angelica Rocha de Freitas Melhem Mariana Abe Vicente Cavagnari Caryna Eurich Mazur Dalton Luiz Schiessel |
| author_sort | Elis Regina Muller Ramos |
| collection | DOAJ |
| description |
Sarcopenia is a progressive skeletal muscle disorder characterized by reduced strength and quality. Pathophysiological mechanisms, clinical aspects, and nutritional points were related to sarcopenia in COVID-19 found in skeletal muscle during and after the disease course, which corroborated the development of adverse events. Declining physical activity, insufficient protein intake, and worsened proinflammatory response have been shown to have negative consequences on muscle protein synthesis, potentiating the risk of acute sarcopenia. Obesity sarcopenia has also been shown to worsen the prognosis of patients with SARS-CoV-2. Nutritional rehabilitation is used to prevent or minimize the development of acute sarcopenia. Dietary recommendations include increased energy supply and protein intake of 1.2 to 2.0 g/kg of body weight. Evidence suggests that aging with sedentary behaviors, pathophysiological changes, and inflammation alter body composition. In addition, nutritional deficiencies are predictors and aggravators of acute sarcopenia in COVID-19.
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| first_indexed | 2024-03-11T22:51:48Z |
| format | Article |
| id | doaj.art-8599c71280264d4c8e6c5496ede65273 |
| institution | Directory Open Access Journal |
| issn | 2236-3785 |
| language | English |
| last_indexed | 2024-03-11T22:51:48Z |
| publishDate | 2023-09-01 |
| publisher | Hospital de Clínicas de Itajubá |
| record_format | Article |
| series | Revista Ciências em Saúde |
| spelling | doaj.art-8599c71280264d4c8e6c5496ede652732023-09-22T01:21:31ZengHospital de Clínicas de ItajubáRevista Ciências em Saúde2236-37852023-09-0113310.21876/rcshci.v13i3.1436COVID-19 related to sarcopenia: Current perspectives on etiology, clinical implications, and nutritional rehabilitationElis Regina Muller Ramos0Anderson Matheus Oliveira Haas Verdi1Stephane Janaina de Moura Escobar2Angelica Rocha de Freitas Melhem3Mariana Abe Vicente Cavagnari4Caryna Eurich Mazur5Dalton Luiz Schiessel6Universidade Estadual do Centro-Oeste - UNICENTROEscola Paulista de Medicina (EPM) da Universidade Federal de São Paulo (UNIFESP)Universidade Estadual do Centro-Oeste - UNICENTROUniversidade Estadual do Centro-Oeste - UNICENTROUniversidade Estadual do Oeste do Paraná, Campus Francisco BeltrãoUniversidade Estadual do Oeste do Paraná, Campus Francisco BeltrãoUniversidade Estadual do Centro-Oeste - UNICENTRO Sarcopenia is a progressive skeletal muscle disorder characterized by reduced strength and quality. Pathophysiological mechanisms, clinical aspects, and nutritional points were related to sarcopenia in COVID-19 found in skeletal muscle during and after the disease course, which corroborated the development of adverse events. Declining physical activity, insufficient protein intake, and worsened proinflammatory response have been shown to have negative consequences on muscle protein synthesis, potentiating the risk of acute sarcopenia. Obesity sarcopenia has also been shown to worsen the prognosis of patients with SARS-CoV-2. Nutritional rehabilitation is used to prevent or minimize the development of acute sarcopenia. Dietary recommendations include increased energy supply and protein intake of 1.2 to 2.0 g/kg of body weight. Evidence suggests that aging with sedentary behaviors, pathophysiological changes, and inflammation alter body composition. In addition, nutritional deficiencies are predictors and aggravators of acute sarcopenia in COVID-19. https://portalrcs.hcitajuba.org.br/index.php/rcsfmit_zero/article/view/1436SarcopeniaSkeletal muscle massInflammationNutritionSARS-CoV 2 |
| spellingShingle | Elis Regina Muller Ramos Anderson Matheus Oliveira Haas Verdi Stephane Janaina de Moura Escobar Angelica Rocha de Freitas Melhem Mariana Abe Vicente Cavagnari Caryna Eurich Mazur Dalton Luiz Schiessel COVID-19 related to sarcopenia: Current perspectives on etiology, clinical implications, and nutritional rehabilitation Revista Ciências em Saúde Sarcopenia Skeletal muscle mass Inflammation Nutrition SARS-CoV 2 |
| title | COVID-19 related to sarcopenia: Current perspectives on etiology, clinical implications, and nutritional rehabilitation |
| title_full | COVID-19 related to sarcopenia: Current perspectives on etiology, clinical implications, and nutritional rehabilitation |
| title_fullStr | COVID-19 related to sarcopenia: Current perspectives on etiology, clinical implications, and nutritional rehabilitation |
| title_full_unstemmed | COVID-19 related to sarcopenia: Current perspectives on etiology, clinical implications, and nutritional rehabilitation |
| title_short | COVID-19 related to sarcopenia: Current perspectives on etiology, clinical implications, and nutritional rehabilitation |
| title_sort | covid 19 related to sarcopenia current perspectives on etiology clinical implications and nutritional rehabilitation |
| topic | Sarcopenia Skeletal muscle mass Inflammation Nutrition SARS-CoV 2 |
| url | https://portalrcs.hcitajuba.org.br/index.php/rcsfmit_zero/article/view/1436 |
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