Unraveling the 2,3-diketo-l-gulonic acid-dependent and -independent impacts of l-ascorbic acid on somatic cell reprogramming

Unraveling the 2,3-diketo-l-gulonic acid-dependent and -independent impacts of l-ascorbic acid on somatic cell reprogramming

Abstract Background l-ascorbic acid (Asc) plays a pivotal role in regulating various biological processes, including somatic cell reprogramming, through multiple pathways. However, it remains unclear whether Asc regulates reprogramming directly or functions through its metabolites. Results Asc exhib...

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Bibliographic Details
Main Authors: Lining Liang, Meiai He, Yixin Zhang, Chenchen Wang, Zhaohui Qin, Qian Li, Tingting Yang, Fei Meng, Yusheng Zhou, Haofei Ge, Weining Song, Shiyu Chen, Linna Dong, Qiwen Ren, Changpeng Li, Lin Guo, Hao Sun, Wei Zhang, Duanqing Pei, Hui Zheng
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Cell & Bioscience
Subjects:
Asc
Metabolite
DKG
TCA cycle
MET
Online Access:https://doi.org/10.1186/s13578-023-01160-x

Internet

https://doi.org/10.1186/s13578-023-01160-x

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