Antimicrobial effect of calcium hydroxide as an intracanal medicament in root canal treatment: a literature review - Part II. in vivo studies

The first part of this study reviewed the characteristics of calcium hydroxide (Ca(OH)2) and summarized the results of in vitro studies related to its antimicrobial effects. The second part of this review covers in vivo studies including human clinical studies and animal studies. The use of Ca(OH)2...

Full description

Bibliographic Details
Main Authors: Dohyun Kim, Euiseong Kim
Format: Article
Language:English
Published: Korean Academy of Conservative Dentistry 2015-02-01
Series:Restorative Dentistry & Endodontics
Online Access:https://doi.org/10.5395/rde.2015.40.2.97
_version_ 1811287501874135040
author Dohyun Kim
Euiseong Kim
author_facet Dohyun Kim
Euiseong Kim
author_sort Dohyun Kim
collection DOAJ
description The first part of this study reviewed the characteristics of calcium hydroxide (Ca(OH)2) and summarized the results of in vitro studies related to its antimicrobial effects. The second part of this review covers in vivo studies including human clinical studies and animal studies. The use of Ca(OH)2 as an intracanal medicament represented better histological results in animal studies. However, human clinical studies showed limited antimicrobial effects that microorganisms were reduced but not eliminated through the treatment, and that some species had resistance to Ca(OH)2. Most of clinical outcome studies supported that there is no improvement in healing of periapical lesions when Ca(OH)2 was applied between appointments. Further studies are required for the antimicrobial effects of Ca(OH)2, and search for the ideal material and technique to completely clean infected root canals should be continued.
first_indexed 2024-04-13T03:19:47Z
format Article
id doaj.art-85aa714bcb2a401197bd70660cfdfc73
institution Directory Open Access Journal
issn 2234-7658
2234-7666
language English
last_indexed 2024-04-13T03:19:47Z
publishDate 2015-02-01
publisher Korean Academy of Conservative Dentistry
record_format Article
series Restorative Dentistry & Endodontics
spelling doaj.art-85aa714bcb2a401197bd70660cfdfc732022-12-22T03:04:48ZengKorean Academy of Conservative DentistryRestorative Dentistry & Endodontics2234-76582234-76662015-02-014029710310.5395/rde.2015.40.2.97Antimicrobial effect of calcium hydroxide as an intracanal medicament in root canal treatment: a literature review - Part II. in vivo studiesDohyun Kim0Euiseong Kim1Microscope Center, Department of Conservative Dentistry and Oral Science Research Center, Yonsei University College of Dentistry, Seoul, Korea.Microscope Center, Department of Conservative Dentistry and Oral Science Research Center, Yonsei University College of Dentistry, Seoul, Korea.The first part of this study reviewed the characteristics of calcium hydroxide (Ca(OH)2) and summarized the results of in vitro studies related to its antimicrobial effects. The second part of this review covers in vivo studies including human clinical studies and animal studies. The use of Ca(OH)2 as an intracanal medicament represented better histological results in animal studies. However, human clinical studies showed limited antimicrobial effects that microorganisms were reduced but not eliminated through the treatment, and that some species had resistance to Ca(OH)2. Most of clinical outcome studies supported that there is no improvement in healing of periapical lesions when Ca(OH)2 was applied between appointments. Further studies are required for the antimicrobial effects of Ca(OH)2, and search for the ideal material and technique to completely clean infected root canals should be continued.https://doi.org/10.5395/rde.2015.40.2.97
spellingShingle Dohyun Kim
Euiseong Kim
Antimicrobial effect of calcium hydroxide as an intracanal medicament in root canal treatment: a literature review - Part II. in vivo studies
Restorative Dentistry & Endodontics
title Antimicrobial effect of calcium hydroxide as an intracanal medicament in root canal treatment: a literature review - Part II. in vivo studies
title_full Antimicrobial effect of calcium hydroxide as an intracanal medicament in root canal treatment: a literature review - Part II. in vivo studies
title_fullStr Antimicrobial effect of calcium hydroxide as an intracanal medicament in root canal treatment: a literature review - Part II. in vivo studies
title_full_unstemmed Antimicrobial effect of calcium hydroxide as an intracanal medicament in root canal treatment: a literature review - Part II. in vivo studies
title_short Antimicrobial effect of calcium hydroxide as an intracanal medicament in root canal treatment: a literature review - Part II. in vivo studies
title_sort antimicrobial effect of calcium hydroxide as an intracanal medicament in root canal treatment a literature review part ii in vivo studies
url https://doi.org/10.5395/rde.2015.40.2.97
work_keys_str_mv AT dohyunkim antimicrobialeffectofcalciumhydroxideasanintracanalmedicamentinrootcanaltreatmentaliteraturereviewpartiiinvivostudies
AT euiseongkim antimicrobialeffectofcalciumhydroxideasanintracanalmedicamentinrootcanaltreatmentaliteraturereviewpartiiinvivostudies