Metabolites and Genes behind Cardiac Metabolic Remodeling in Mice with Type 1 Diabetes Mellitus

Metabolites and Genes behind Cardiac Metabolic Remodeling in Mice with Type 1 Diabetes Mellitus

Metabolic remodeling is at the heart of diabetic cardiomyopathy. High glycemic fluctuations increase metabolic stress in the type 1 diabetes mellitus (T1DM) heart. There is a lack of understanding on how metabolites and genes affect metabolic remodeling in the T1DM heart. We hypothesize that differe...

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Bibliographic Details
Main Authors: Tyler N. Kambis, Hamid R. Shahshahan, Paras K. Mishra
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:International Journal of Molecular Sciences
Subjects:
beta-oxidation
diabetic cardiomyopathy
fatty acid
genomics
ketogenesis
ketolysis
Online Access:https://www.mdpi.com/1422-0067/23/3/1392

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