Case report<Br>Graves’ thyrotoxicosis in a patient with metastatic differentiated thyroid carcinoma and chronic lymphocytic leukaemia (CLL)
Thyrotoxicosis is rare in patients with thyroid carcinoma. A case is reported of a 66-year-old woman with Graves’ disease, papillary thyroid carcinoma (PTC) with pulmonary metastases and chronic lymphocytic leukaemia (CLL). After thyroidectomy and antithyroid drug (ATD) withdrawal, thyrotoxicosis re...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Termedia Publishing House
2007-06-01
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| Series: | Archives of Medical Science |
| Subjects: | |
| Online Access: | http://www.termedia.pl/magazine.php?magazine_id=19&article_id=8492&magazine_subpage=FULL_TEXT |
| _version_ | 1819081944266178560 |
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| author | Jacek Makarewicz Sławomir Mikosiński Antoni Rutkowski Zbigniew Adamczewski Andrzej Lewiński |
| author_facet | Jacek Makarewicz Sławomir Mikosiński Antoni Rutkowski Zbigniew Adamczewski Andrzej Lewiński |
| author_sort | Jacek Makarewicz |
| collection | DOAJ |
| description | Thyrotoxicosis is rare in patients with thyroid carcinoma. A case is reported of a 66-year-old woman with Graves’ disease, papillary thyroid carcinoma (PTC) with pulmonary metastases and chronic lymphocytic leukaemia (CLL). After thyroidectomy and antithyroid drug (ATD) withdrawal, thyrotoxicosis recurred. Treatment with ATD and 131I (six doses, 36.3 GBq in total) resulted in permanent hypothyroidism and significant destruction of lung metastases. The course of CLL was mild, but transient anaemia and thrombocytopenia were observed after 131I therapy. Pathomechanisms of thyrotoxicosis in patients with metastatic thyroid carcinoma, its treatment and its relation to CLL are presented. |
| first_indexed | 2024-12-21T20:08:49Z |
| format | Article |
| id | doaj.art-85b41f5d62924e61909e3b6b3eda5587 |
| institution | Directory Open Access Journal |
| issn | 1734-1922 |
| language | English |
| last_indexed | 2024-12-21T20:08:49Z |
| publishDate | 2007-06-01 |
| publisher | Termedia Publishing House |
| record_format | Article |
| series | Archives of Medical Science |
| spelling | doaj.art-85b41f5d62924e61909e3b6b3eda55872022-12-21T18:51:47ZengTermedia Publishing HouseArchives of Medical Science1734-19222007-06-0132179184Case report<Br>Graves’ thyrotoxicosis in a patient with metastatic differentiated thyroid carcinoma and chronic lymphocytic leukaemia (CLL)Jacek MakarewiczSławomir MikosińskiAntoni RutkowskiZbigniew AdamczewskiAndrzej LewińskiThyrotoxicosis is rare in patients with thyroid carcinoma. A case is reported of a 66-year-old woman with Graves’ disease, papillary thyroid carcinoma (PTC) with pulmonary metastases and chronic lymphocytic leukaemia (CLL). After thyroidectomy and antithyroid drug (ATD) withdrawal, thyrotoxicosis recurred. Treatment with ATD and 131I (six doses, 36.3 GBq in total) resulted in permanent hypothyroidism and significant destruction of lung metastases. The course of CLL was mild, but transient anaemia and thrombocytopenia were observed after 131I therapy. Pathomechanisms of thyrotoxicosis in patients with metastatic thyroid carcinoma, its treatment and its relation to CLL are presented.http://www.termedia.pl/magazine.php?magazine_id=19&article_id=8492&magazine_subpage=FULL_TEXTthyroid carcinomathyrotoxicosismetastasesradioiodine therapychronic lymphocytic leukaemia |
| spellingShingle | Jacek Makarewicz Sławomir Mikosiński Antoni Rutkowski Zbigniew Adamczewski Andrzej Lewiński Case report<Br>Graves’ thyrotoxicosis in a patient with metastatic differentiated thyroid carcinoma and chronic lymphocytic leukaemia (CLL) Archives of Medical Science thyroid carcinoma thyrotoxicosis metastases radioiodine therapy chronic lymphocytic leukaemia |
| title | Case report<Br>Graves’ thyrotoxicosis in a patient with metastatic differentiated thyroid carcinoma and chronic lymphocytic leukaemia (CLL) |
| title_full | Case report<Br>Graves’ thyrotoxicosis in a patient with metastatic differentiated thyroid carcinoma and chronic lymphocytic leukaemia (CLL) |
| title_fullStr | Case report<Br>Graves’ thyrotoxicosis in a patient with metastatic differentiated thyroid carcinoma and chronic lymphocytic leukaemia (CLL) |
| title_full_unstemmed | Case report<Br>Graves’ thyrotoxicosis in a patient with metastatic differentiated thyroid carcinoma and chronic lymphocytic leukaemia (CLL) |
| title_short | Case report<Br>Graves’ thyrotoxicosis in a patient with metastatic differentiated thyroid carcinoma and chronic lymphocytic leukaemia (CLL) |
| title_sort | case report br graves thyrotoxicosis in a patient with metastatic differentiated thyroid carcinoma and chronic lymphocytic leukaemia cll |
| topic | thyroid carcinoma thyrotoxicosis metastases radioiodine therapy chronic lymphocytic leukaemia |
| url | http://www.termedia.pl/magazine.php?magazine_id=19&article_id=8492&magazine_subpage=FULL_TEXT |
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