Long‐term daily oral administration of intestinal permeation enhancers is safe and effective in mice

Abstract Although protein drugs are powerful biologic therapeutics, they cannot be delivered orally because their large size and hydrophilicity limit their absorption across the intestinal epithelium. One potential solution is the incorporation of permeation enhancers into oral protein formulations;...

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Bibliographic Details
Main Authors: Katherine C. Fein, John P. Gleeson, Kyle Cochran, Nicholas G. Lamson, Rose Doerfler, Jilian R. Melamed, Kathryn A. Whitehead
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Bioengineering & Translational Medicine
Subjects:
Online Access:https://doi.org/10.1002/btm2.10342

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