A LATS biosensor screen identifies VEGFR as a regulator of the Hippo pathway in angiogenesis

A LATS biosensor screen identifies VEGFR as a regulator of the Hippo pathway in angiogenesis

The Hippo pathway is a major orchestrator of organ development and homeostasis. Here Azad and colleagues develop a biosensor to monitor the activity of the Hippo pathway component LATS and identify VEGF signalling as an upstream regulator of LATS, supporting a role for Hippo signalling during angiog...

Full description

Bibliographic Details
Main Authors: T. Azad, H. J. Janse van Rensburg, E. D. Lightbody, B. Neveu, A. Champagne, A. Ghaffari, V. R. Kay, Y. Hao, H. Shen, B. Yeung, B. A. Croy, K. L. Guan, F. Pouliot, J. Zhang, C. J. B. Nicol, X. Yang
Format: Article
Language:English
Published: Nature Portfolio 2018-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-03278-w

Similar Items

Similar Items