MicroRNA Implication in Cancer
MicroRNAs (miRNA) are a new class of posttranscriptional regulators. These small non-coding RNAs regulate the expression of target mRNA transcripts and are linked to several human disease such as Alzheimer, cancer or heart disease. But it has been the cancer disease which has experimented the major...
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| Format: | Article |
| Language: | English |
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Society of Land Measurements and Cadastre from Transylvania (SMTCT)
2010-03-01
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| Series: | Notulae Scientia Biologicae |
| Online Access: | http://notulaebiologicae.ro/index.php/nsb/article/view/4566 |
| _version_ | 1818507304952135680 |
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| author | Iker BADIOLA |
| author_facet | Iker BADIOLA |
| author_sort | Iker BADIOLA |
| collection | DOAJ |
| description | MicroRNAs (miRNA) are a new class of posttranscriptional regulators. These small non-coding RNAs regulate the expression of target mRNA transcripts and are linked to several human disease such as Alzheimer, cancer or heart disease. But it has been the cancer disease which has experimented the major number of studies of miRNA linked to the disease progression. In the last years it has been reported the deregulation pattern of the miRNAs in malignant cells which have disrupted the control of the proliferation, differentiation or apoptosis. The evidence of the presence of specific miRNA deregulated in concrete cancer types has become the miRNAs like possible biomarkers and therapeutic targets. The specific miRNA patterns deregulated in concrete cancer cell types open new opportunities to the diagnosis and therapy. |
| first_indexed | 2024-12-10T22:16:41Z |
| format | Article |
| id | doaj.art-85bbfebc23124917907b1983eb691293 |
| institution | Directory Open Access Journal |
| issn | 2067-3205 2067-3264 |
| language | English |
| last_indexed | 2024-12-10T22:16:41Z |
| publishDate | 2010-03-01 |
| publisher | Society of Land Measurements and Cadastre from Transylvania (SMTCT) |
| record_format | Article |
| series | Notulae Scientia Biologicae |
| spelling | doaj.art-85bbfebc23124917907b1983eb6912932022-12-22T01:31:27ZengSociety of Land Measurements and Cadastre from Transylvania (SMTCT)Notulae Scientia Biologicae2067-32052067-32642010-03-012107134801MicroRNA Implication in CancerIker BADIOLA0Innovative Technologies in Biological Systems (INNOPROT), Parque Tecnol�gico de Bizkaia Ed. 502-1�, 48160, DerioMicroRNAs (miRNA) are a new class of posttranscriptional regulators. These small non-coding RNAs regulate the expression of target mRNA transcripts and are linked to several human disease such as Alzheimer, cancer or heart disease. But it has been the cancer disease which has experimented the major number of studies of miRNA linked to the disease progression. In the last years it has been reported the deregulation pattern of the miRNAs in malignant cells which have disrupted the control of the proliferation, differentiation or apoptosis. The evidence of the presence of specific miRNA deregulated in concrete cancer types has become the miRNAs like possible biomarkers and therapeutic targets. The specific miRNA patterns deregulated in concrete cancer cell types open new opportunities to the diagnosis and therapy.http://notulaebiologicae.ro/index.php/nsb/article/view/4566 |
| spellingShingle | Iker BADIOLA MicroRNA Implication in Cancer Notulae Scientia Biologicae |
| title | MicroRNA Implication in Cancer |
| title_full | MicroRNA Implication in Cancer |
| title_fullStr | MicroRNA Implication in Cancer |
| title_full_unstemmed | MicroRNA Implication in Cancer |
| title_short | MicroRNA Implication in Cancer |
| title_sort | microrna implication in cancer |
| url | http://notulaebiologicae.ro/index.php/nsb/article/view/4566 |
| work_keys_str_mv | AT ikerbadiola micrornaimplicationincancer |