Auxiliary Liver Transplantation as a Transient Treatment for Acute Liver Failure: Two Cases

Introduction: Acute liver failure is an uncommon condition associated with a high mortality. Most patients do not survive without liver transplantation. In the last decades, auxiliary liver transplantation has emerged as a therapeutic option. Clinical Case: The authors present two cases of acute liv...

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Main Authors: David N. Perdigoto, Luís Tomé, Dulce Diogo, José Ferrão, Ricardo Martins, Pedro Oliveira, Guilherme Tralhão, Emanuel Furtado
Format: Article
Language:English
Published: Karger Publishers 2018-03-01
Series:GE: Portuguese Journal of Gastroenterology
Subjects:
Online Access:https://www.karger.com/Article/FullText/487155
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author David N. Perdigoto
Luís Tomé
Dulce Diogo
José Ferrão
Ricardo Martins
Pedro Oliveira
Guilherme Tralhão
Emanuel Furtado
author_facet David N. Perdigoto
Luís Tomé
Dulce Diogo
José Ferrão
Ricardo Martins
Pedro Oliveira
Guilherme Tralhão
Emanuel Furtado
author_sort David N. Perdigoto
collection DOAJ
description Introduction: Acute liver failure is an uncommon condition associated with a high mortality. Most patients do not survive without liver transplantation. In the last decades, auxiliary liver transplantation has emerged as a therapeutic option. Clinical Case: The authors present two cases of acute liver failure that required liver transplantation. Given the patients’ young age and the preserved macroscopic liver pattern evaluated in surgery, auxiliary liver transplantation was executed using different surgical approaches. Afterwards, following confirmed full native liver regeneration, the patients were submitted to auxiliary liver hepatectomy, which was accomplished without complications. Conclusion: Auxiliary liver transplantation can be regarded as an effective temporary treatment for acute liver failure in selected cases, allowing an immunosuppression-free life.
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spelling doaj.art-85bf9e2811d64873b5ccc4d104b647662022-12-21T17:17:53ZengKarger PublishersGE: Portuguese Journal of Gastroenterology2341-45452387-19542018-03-0110.1159/000487155487155Auxiliary Liver Transplantation as a Transient Treatment for Acute Liver Failure: Two CasesDavid N. PerdigotoLuís ToméDulce DiogoJosé FerrãoRicardo MartinsPedro OliveiraGuilherme TralhãoEmanuel FurtadoIntroduction: Acute liver failure is an uncommon condition associated with a high mortality. Most patients do not survive without liver transplantation. In the last decades, auxiliary liver transplantation has emerged as a therapeutic option. Clinical Case: The authors present two cases of acute liver failure that required liver transplantation. Given the patients’ young age and the preserved macroscopic liver pattern evaluated in surgery, auxiliary liver transplantation was executed using different surgical approaches. Afterwards, following confirmed full native liver regeneration, the patients were submitted to auxiliary liver hepatectomy, which was accomplished without complications. Conclusion: Auxiliary liver transplantation can be regarded as an effective temporary treatment for acute liver failure in selected cases, allowing an immunosuppression-free life.https://www.karger.com/Article/FullText/487155Acute liver failureLiver transplantationAuxiliary liver transplantationImmunosuppression
spellingShingle David N. Perdigoto
Luís Tomé
Dulce Diogo
José Ferrão
Ricardo Martins
Pedro Oliveira
Guilherme Tralhão
Emanuel Furtado
Auxiliary Liver Transplantation as a Transient Treatment for Acute Liver Failure: Two Cases
GE: Portuguese Journal of Gastroenterology
Acute liver failure
Liver transplantation
Auxiliary liver transplantation
Immunosuppression
title Auxiliary Liver Transplantation as a Transient Treatment for Acute Liver Failure: Two Cases
title_full Auxiliary Liver Transplantation as a Transient Treatment for Acute Liver Failure: Two Cases
title_fullStr Auxiliary Liver Transplantation as a Transient Treatment for Acute Liver Failure: Two Cases
title_full_unstemmed Auxiliary Liver Transplantation as a Transient Treatment for Acute Liver Failure: Two Cases
title_short Auxiliary Liver Transplantation as a Transient Treatment for Acute Liver Failure: Two Cases
title_sort auxiliary liver transplantation as a transient treatment for acute liver failure two cases
topic Acute liver failure
Liver transplantation
Auxiliary liver transplantation
Immunosuppression
url https://www.karger.com/Article/FullText/487155
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