Auxiliary Liver Transplantation as a Transient Treatment for Acute Liver Failure: Two Cases
Introduction: Acute liver failure is an uncommon condition associated with a high mortality. Most patients do not survive without liver transplantation. In the last decades, auxiliary liver transplantation has emerged as a therapeutic option. Clinical Case: The authors present two cases of acute liv...
Main Authors: | , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Karger Publishers
2018-03-01
|
Series: | GE: Portuguese Journal of Gastroenterology |
Subjects: | |
Online Access: | https://www.karger.com/Article/FullText/487155 |
_version_ | 1819289563664744448 |
---|---|
author | David N. Perdigoto Luís Tomé Dulce Diogo José Ferrão Ricardo Martins Pedro Oliveira Guilherme Tralhão Emanuel Furtado |
author_facet | David N. Perdigoto Luís Tomé Dulce Diogo José Ferrão Ricardo Martins Pedro Oliveira Guilherme Tralhão Emanuel Furtado |
author_sort | David N. Perdigoto |
collection | DOAJ |
description | Introduction: Acute liver failure is an uncommon condition associated with a high mortality. Most patients do not survive without liver transplantation. In the last decades, auxiliary liver transplantation has emerged as a therapeutic option. Clinical Case: The authors present two cases of acute liver failure that required liver transplantation. Given the patients’ young age and the preserved macroscopic liver pattern evaluated in surgery, auxiliary liver transplantation was executed using different surgical approaches. Afterwards, following confirmed full native liver regeneration, the patients were submitted to auxiliary liver hepatectomy, which was accomplished without complications. Conclusion: Auxiliary liver transplantation can be regarded as an effective temporary treatment for acute liver failure in selected cases, allowing an immunosuppression-free life. |
first_indexed | 2024-12-24T03:08:50Z |
format | Article |
id | doaj.art-85bf9e2811d64873b5ccc4d104b64766 |
institution | Directory Open Access Journal |
issn | 2341-4545 2387-1954 |
language | English |
last_indexed | 2024-12-24T03:08:50Z |
publishDate | 2018-03-01 |
publisher | Karger Publishers |
record_format | Article |
series | GE: Portuguese Journal of Gastroenterology |
spelling | doaj.art-85bf9e2811d64873b5ccc4d104b647662022-12-21T17:17:53ZengKarger PublishersGE: Portuguese Journal of Gastroenterology2341-45452387-19542018-03-0110.1159/000487155487155Auxiliary Liver Transplantation as a Transient Treatment for Acute Liver Failure: Two CasesDavid N. PerdigotoLuís ToméDulce DiogoJosé FerrãoRicardo MartinsPedro OliveiraGuilherme TralhãoEmanuel FurtadoIntroduction: Acute liver failure is an uncommon condition associated with a high mortality. Most patients do not survive without liver transplantation. In the last decades, auxiliary liver transplantation has emerged as a therapeutic option. Clinical Case: The authors present two cases of acute liver failure that required liver transplantation. Given the patients’ young age and the preserved macroscopic liver pattern evaluated in surgery, auxiliary liver transplantation was executed using different surgical approaches. Afterwards, following confirmed full native liver regeneration, the patients were submitted to auxiliary liver hepatectomy, which was accomplished without complications. Conclusion: Auxiliary liver transplantation can be regarded as an effective temporary treatment for acute liver failure in selected cases, allowing an immunosuppression-free life.https://www.karger.com/Article/FullText/487155Acute liver failureLiver transplantationAuxiliary liver transplantationImmunosuppression |
spellingShingle | David N. Perdigoto Luís Tomé Dulce Diogo José Ferrão Ricardo Martins Pedro Oliveira Guilherme Tralhão Emanuel Furtado Auxiliary Liver Transplantation as a Transient Treatment for Acute Liver Failure: Two Cases GE: Portuguese Journal of Gastroenterology Acute liver failure Liver transplantation Auxiliary liver transplantation Immunosuppression |
title | Auxiliary Liver Transplantation as a Transient Treatment for Acute Liver Failure: Two Cases |
title_full | Auxiliary Liver Transplantation as a Transient Treatment for Acute Liver Failure: Two Cases |
title_fullStr | Auxiliary Liver Transplantation as a Transient Treatment for Acute Liver Failure: Two Cases |
title_full_unstemmed | Auxiliary Liver Transplantation as a Transient Treatment for Acute Liver Failure: Two Cases |
title_short | Auxiliary Liver Transplantation as a Transient Treatment for Acute Liver Failure: Two Cases |
title_sort | auxiliary liver transplantation as a transient treatment for acute liver failure two cases |
topic | Acute liver failure Liver transplantation Auxiliary liver transplantation Immunosuppression |
url | https://www.karger.com/Article/FullText/487155 |
work_keys_str_mv | AT davidnperdigoto auxiliarylivertransplantationasatransienttreatmentforacuteliverfailuretwocases AT luistome auxiliarylivertransplantationasatransienttreatmentforacuteliverfailuretwocases AT dulcediogo auxiliarylivertransplantationasatransienttreatmentforacuteliverfailuretwocases AT joseferrao auxiliarylivertransplantationasatransienttreatmentforacuteliverfailuretwocases AT ricardomartins auxiliarylivertransplantationasatransienttreatmentforacuteliverfailuretwocases AT pedrooliveira auxiliarylivertransplantationasatransienttreatmentforacuteliverfailuretwocases AT guilhermetralhao auxiliarylivertransplantationasatransienttreatmentforacuteliverfailuretwocases AT emanuelfurtado auxiliarylivertransplantationasatransienttreatmentforacuteliverfailuretwocases |