Progression and regression of left ventricular hypertrophy and myocardial fibrosis in a mouse model of hypertension and concomitant cardiomyopathy

Progression and regression of left ventricular hypertrophy and myocardial fibrosis in a mouse model of hypertension and concomitant cardiomyopathy

Abstract Background Myocardial fibrosis is observed in multiple cardiac conditions including hypertension and aortic stenosis. Excessive fibrosis is associated with adverse clinical outcomes, but longitudinal human data regarding changes in left ventricular remodelling and fibrosis over time are spa...

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Bibliographic Details
Main Authors: Jacek Kwiecinski, Ross J. Lennen, Gillian A. Gray, Gary Borthwick, Lyndsey Boswell, Andrew H. Baker, David E. Newby, Marc R. Dweck, Maurits A. Jansen
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Journal of Cardiovascular Magnetic Resonance
Subjects:
Hypertension
Cardiovascular magnetic resonance 
ECV
T1-mapping
Online Access:http://link.springer.com/article/10.1186/s12968-020-00655-7

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