Tuberous Sclerosis Complex Associated with Heterotopic Ossification in a Young Girl
Tuberous sclerosis complex (TSC) is a multisystem disorder resulting in hamartomatous lesions. Despite diverse manifestations, skeletal muscular comorbidity is rarely reported in TSC. We report a 2-year-old girl with TSC who suffered from multiple subcutaneous masses over the paraspinal and bilatera...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2014-02-01
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| Series: | Pediatrics and Neonatology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1875957212002112 |
| _version_ | 1819054831084503040 |
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| author | Teck-King Tan Fong-Lin Chen Ji-Nan Sheu Shan-Ming Chen Hsin-Hui Huang Jeng-Dau Tsai |
| author_facet | Teck-King Tan Fong-Lin Chen Ji-Nan Sheu Shan-Ming Chen Hsin-Hui Huang Jeng-Dau Tsai |
| author_sort | Teck-King Tan |
| collection | DOAJ |
| description | Tuberous sclerosis complex (TSC) is a multisystem disorder resulting in hamartomatous lesions. Despite diverse manifestations, skeletal muscular comorbidity is rarely reported in TSC. We report a 2-year-old girl with TSC who suffered from multiple subcutaneous masses over the paraspinal and bilateral scapular areas, which caused disabling pain on any passive movement. Three-dimensional computed tomography scanning revealed multiple calcifications that were consequently diagnosed as fibrodysplasia ossificans progressiva. Such imaging features should be evaluated cautiously to avoid unnecessary surgical intervention and biopsy that may worsen the condition. |
| first_indexed | 2024-12-21T12:57:52Z |
| format | Article |
| id | doaj.art-85d08fdb20df47a9bd5c0f02c784c865 |
| institution | Directory Open Access Journal |
| issn | 1875-9572 |
| language | English |
| last_indexed | 2024-12-21T12:57:52Z |
| publishDate | 2014-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Pediatrics and Neonatology |
| spelling | doaj.art-85d08fdb20df47a9bd5c0f02c784c8652022-12-21T19:03:16ZengElsevierPediatrics and Neonatology1875-95722014-02-01551656710.1016/j.pedneo.2012.12.002Tuberous Sclerosis Complex Associated with Heterotopic Ossification in a Young GirlTeck-King Tan0Fong-Lin Chen1Ji-Nan Sheu2Shan-Ming Chen3Hsin-Hui Huang4Jeng-Dau Tsai5Department of Pediatrics, Chung Shan Medical University Hospital, Taichung, TaiwanDepartment of Pediatrics, Chung Shan Medical University Hospital, Taichung, TaiwanDepartment of Pediatrics, Chung Shan Medical University Hospital, Taichung, TaiwanDepartment of Pediatrics, Chung Shan Medical University Hospital, Taichung, TaiwanDepartment of Medical Imaging, Chung Shan Medical University Hospital, Taichung, TaiwanDepartment of Pediatrics, Chung Shan Medical University Hospital, Taichung, TaiwanTuberous sclerosis complex (TSC) is a multisystem disorder resulting in hamartomatous lesions. Despite diverse manifestations, skeletal muscular comorbidity is rarely reported in TSC. We report a 2-year-old girl with TSC who suffered from multiple subcutaneous masses over the paraspinal and bilateral scapular areas, which caused disabling pain on any passive movement. Three-dimensional computed tomography scanning revealed multiple calcifications that were consequently diagnosed as fibrodysplasia ossificans progressiva. Such imaging features should be evaluated cautiously to avoid unnecessary surgical intervention and biopsy that may worsen the condition.http://www.sciencedirect.com/science/article/pii/S1875957212002112fibrodysplasia ossificans progressiveheterotopic ossificanstuberous sclerosis complex |
| spellingShingle | Teck-King Tan Fong-Lin Chen Ji-Nan Sheu Shan-Ming Chen Hsin-Hui Huang Jeng-Dau Tsai Tuberous Sclerosis Complex Associated with Heterotopic Ossification in a Young Girl Pediatrics and Neonatology fibrodysplasia ossificans progressive heterotopic ossificans tuberous sclerosis complex |
| title | Tuberous Sclerosis Complex Associated with Heterotopic Ossification in a Young Girl |
| title_full | Tuberous Sclerosis Complex Associated with Heterotopic Ossification in a Young Girl |
| title_fullStr | Tuberous Sclerosis Complex Associated with Heterotopic Ossification in a Young Girl |
| title_full_unstemmed | Tuberous Sclerosis Complex Associated with Heterotopic Ossification in a Young Girl |
| title_short | Tuberous Sclerosis Complex Associated with Heterotopic Ossification in a Young Girl |
| title_sort | tuberous sclerosis complex associated with heterotopic ossification in a young girl |
| topic | fibrodysplasia ossificans progressive heterotopic ossificans tuberous sclerosis complex |
| url | http://www.sciencedirect.com/science/article/pii/S1875957212002112 |
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