Platypnea-Orthodeoxia Syndrome Manifesting as an Early Complication after Lower Bilobectomy
Platypnea-orthodeoxia syndrome (POS) is an uncommon clinical condition characterized by orthostatic dyspnea and hypoxemia. The case of a female patient who manifested postoperative episodes of sudden oxygen desaturation, dyspnea, and systemic arterial hypotension following lower bilobectomy for lung...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-04-01
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| Series: | Surgeries |
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| Online Access: | https://www.mdpi.com/2673-4095/4/2/18 |
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| author | Carmelina C. Zirafa Alessandra Lenzini Paolo Spontoni Claudia Cariello Luca Doroni Adrea Pieroni Anna S. Petronio Franca Melfi |
| author_facet | Carmelina C. Zirafa Alessandra Lenzini Paolo Spontoni Claudia Cariello Luca Doroni Adrea Pieroni Anna S. Petronio Franca Melfi |
| author_sort | Carmelina C. Zirafa |
| collection | DOAJ |
| description | Platypnea-orthodeoxia syndrome (POS) is an uncommon clinical condition characterized by orthostatic dyspnea and hypoxemia. The case of a female patient who manifested postoperative episodes of sudden oxygen desaturation, dyspnea, and systemic arterial hypotension following lower bilobectomy for lung adenocarcinoma was reported. After meticulous clinical investigations, the patient proved to be affected by a rare form of postural dyspnea: platypnea-orthodeoxia syndrome, a clinical disorder described in the middle of the last century. The pathophysiology was found in an intracardiac mechanism of right-to-left blood shunt, combined with lung and chest wall modification. Atrial septal defect, such as patent foramen ovale (PFO), is a common cause of platypnea-orthodeoxia syndrome; the rescue closure of PFO usually allows for an immediate and consistent improvement of the symptoms. |
| first_indexed | 2024-03-11T01:56:05Z |
| format | Article |
| id | doaj.art-85d25699a3404519bddaf858fe4285fa |
| institution | Directory Open Access Journal |
| issn | 2673-4095 |
| language | English |
| last_indexed | 2024-03-11T01:56:05Z |
| publishDate | 2023-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Surgeries |
| spelling | doaj.art-85d25699a3404519bddaf858fe4285fa2023-11-18T12:39:37ZengMDPI AGSurgeries2673-40952023-04-014216417410.3390/surgeries4020018Platypnea-Orthodeoxia Syndrome Manifesting as an Early Complication after Lower BilobectomyCarmelina C. Zirafa0Alessandra Lenzini1Paolo Spontoni2Claudia Cariello3Luca Doroni4Adrea Pieroni5Anna S. Petronio6Franca Melfi7Minimally Invasive and Robotic Thoracic Surgery Division, Robotic Multispecialty Center of Surgery, University Hospital of Pisa, 56124 Pisa, ItalyThoracic Surgery Unit, Department of Surgical, Medical, Molecular, Pathology and Critical Care, University Hospital of Pisa, 56124 Pisa, ItalyCardiac Catheterization Laboratory, Cardiothoracic and Vascular Department, University Hospital of Pisa, 56124 Pisa, ItalyCardiothoracic and Vascular Anaesthesia and Intensive Care Unit, Department of Anesthesia and Critical Care Medicine, University Hospital of Pisa, 56124 Pisa, ItalyCardiothoracic and Vascular Anaesthesia and Intensive Care Unit, Department of Anesthesia and Critical Care Medicine, University Hospital of Pisa, 56124 Pisa, ItalyCardiac Catheterization Laboratory, Cardiothoracic and Vascular Department, University Hospital of Pisa, 56124 Pisa, ItalyCardiac Catheterization Laboratory, Cardiothoracic and Vascular Department, University Hospital of Pisa, 56124 Pisa, ItalyMinimally Invasive and Robotic Thoracic Surgery Division, Robotic Multispecialty Center of Surgery, University Hospital of Pisa, 56124 Pisa, ItalyPlatypnea-orthodeoxia syndrome (POS) is an uncommon clinical condition characterized by orthostatic dyspnea and hypoxemia. The case of a female patient who manifested postoperative episodes of sudden oxygen desaturation, dyspnea, and systemic arterial hypotension following lower bilobectomy for lung adenocarcinoma was reported. After meticulous clinical investigations, the patient proved to be affected by a rare form of postural dyspnea: platypnea-orthodeoxia syndrome, a clinical disorder described in the middle of the last century. The pathophysiology was found in an intracardiac mechanism of right-to-left blood shunt, combined with lung and chest wall modification. Atrial septal defect, such as patent foramen ovale (PFO), is a common cause of platypnea-orthodeoxia syndrome; the rescue closure of PFO usually allows for an immediate and consistent improvement of the symptoms.https://www.mdpi.com/2673-4095/4/2/18platypnea-orthodeoxiabilobectomythoracic surgerylung cancerlung resectionoxygen desaturation |
| spellingShingle | Carmelina C. Zirafa Alessandra Lenzini Paolo Spontoni Claudia Cariello Luca Doroni Adrea Pieroni Anna S. Petronio Franca Melfi Platypnea-Orthodeoxia Syndrome Manifesting as an Early Complication after Lower Bilobectomy Surgeries platypnea-orthodeoxia bilobectomy thoracic surgery lung cancer lung resection oxygen desaturation |
| title | Platypnea-Orthodeoxia Syndrome Manifesting as an Early Complication after Lower Bilobectomy |
| title_full | Platypnea-Orthodeoxia Syndrome Manifesting as an Early Complication after Lower Bilobectomy |
| title_fullStr | Platypnea-Orthodeoxia Syndrome Manifesting as an Early Complication after Lower Bilobectomy |
| title_full_unstemmed | Platypnea-Orthodeoxia Syndrome Manifesting as an Early Complication after Lower Bilobectomy |
| title_short | Platypnea-Orthodeoxia Syndrome Manifesting as an Early Complication after Lower Bilobectomy |
| title_sort | platypnea orthodeoxia syndrome manifesting as an early complication after lower bilobectomy |
| topic | platypnea-orthodeoxia bilobectomy thoracic surgery lung cancer lung resection oxygen desaturation |
| url | https://www.mdpi.com/2673-4095/4/2/18 |
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