4.4 Å Resolution Cryo-EM structure of human mTOR Complex 1

4.4 Å Resolution Cryo-EM structure of human mTOR Complex 1

ABSTRACT Mechanistic target of rapamycin (mTOR) complex 1 (mTORC1) integrates signals from growth factors, cellular energy levels, stress and amino acids to control cell growth and proliferation through regulating translation, autophagy and metabolism. Here we determined the cryo-electron microscopy...

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Bibliographic Details
Main Authors: Huirong Yang, Jia Wang, Mengjie Liu, Xizi Chen, Min Huang, Dan Tan, Meng-Qiu Dong, Catherine C. L. Wong, Jiawei Wang, Yanhui Xu, Hong-Wei Wang
Format: Article
Language:English
Published: Oxford University Press 2016-12-01
Series:Protein & Cell
Subjects:
mTORC1
structure
cryo-electron microscopy
Online Access:http://link.springer.com/article/10.1007/s13238-016-0346-6

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