Covering All the Bases in Genetics: Simple Shorthands and Diagrams for Teaching Base Pairing to Biology Undergraduates

Explaining base pairing is an important element in teaching undergraduate genetics. I propose a teaching approach that aims to close the gap between the mantra “A pairs with T, and G pairs with C” and the “intimidating” chemical diagrams. The approach offers a set of simple “shorthands” for the key...

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Main Author: Sergei Kuchin
Format: Article
Language:English
Published: American Society for Microbiology 2011-01-01
Series:Journal of Microbiology & Biology Education
Online Access:https://journals.asm.org/doi/10.1128/jmbe.v12i1.267
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author Sergei Kuchin
author_facet Sergei Kuchin
author_sort Sergei Kuchin
collection DOAJ
description Explaining base pairing is an important element in teaching undergraduate genetics. I propose a teaching approach that aims to close the gap between the mantra “A pairs with T, and G pairs with C” and the “intimidating” chemical diagrams. The approach offers a set of simple “shorthands” for the key bases that can be used to quickly deduce all canonical and wobble pairs that the students need to know. The approach can be further developed to analyze mutagenic mismatch pairing.
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spelling doaj.art-85d8c42a985b4c6aa1c4d0a7ce507caf2022-12-21T20:11:41ZengAmerican Society for MicrobiologyJournal of Microbiology & Biology Education1935-78771935-78852011-01-01121646610.1128/jmbe.v12i1.267Covering All the Bases in Genetics: Simple Shorthands and Diagrams for Teaching Base Pairing to Biology UndergraduatesSergei Kuchin0Department of Biological Sciences, University of Wisconsin-Milwaukee, Milwaukee, WI 53211Explaining base pairing is an important element in teaching undergraduate genetics. I propose a teaching approach that aims to close the gap between the mantra “A pairs with T, and G pairs with C” and the “intimidating” chemical diagrams. The approach offers a set of simple “shorthands” for the key bases that can be used to quickly deduce all canonical and wobble pairs that the students need to know. The approach can be further developed to analyze mutagenic mismatch pairing.https://journals.asm.org/doi/10.1128/jmbe.v12i1.267
spellingShingle Sergei Kuchin
Covering All the Bases in Genetics: Simple Shorthands and Diagrams for Teaching Base Pairing to Biology Undergraduates
Journal of Microbiology & Biology Education
title Covering All the Bases in Genetics: Simple Shorthands and Diagrams for Teaching Base Pairing to Biology Undergraduates
title_full Covering All the Bases in Genetics: Simple Shorthands and Diagrams for Teaching Base Pairing to Biology Undergraduates
title_fullStr Covering All the Bases in Genetics: Simple Shorthands and Diagrams for Teaching Base Pairing to Biology Undergraduates
title_full_unstemmed Covering All the Bases in Genetics: Simple Shorthands and Diagrams for Teaching Base Pairing to Biology Undergraduates
title_short Covering All the Bases in Genetics: Simple Shorthands and Diagrams for Teaching Base Pairing to Biology Undergraduates
title_sort covering all the bases in genetics simple shorthands and diagrams for teaching base pairing to biology undergraduates
url https://journals.asm.org/doi/10.1128/jmbe.v12i1.267
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