Polymer Coated Oncolytic Adenovirus to Selectively Target Hepatocellular Carcinoma Cells

Polymer Coated Oncolytic Adenovirus to Selectively Target Hepatocellular Carcinoma Cells

Despite significant advances in chemotherapy, the overall prognosis of hepatocellular carcinoma (HCC) remains extremely poor. HCC targeting strategies were combined with the tumor cell cytotoxicity of oncolytic viruses (OVs) to develop a more efficient and selective therapeutic system. OVs were coat...

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Bibliographic Details
Main Authors: Mariangela Garofalo, Federica Bellato, Salvatore Magliocca, Alessio Malfanti, Lukasz Kuryk, Beate Rinner, Samuele Negro, Stefano Salmaso, Paolo Caliceti, Francesca Mastrotto
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Pharmaceutics
Subjects:
oncolytic adenovirus
hepatocellular carcinoma
cationic glycopolymers
tumor targeting
cancer therapies
ASGPR
Online Access:https://www.mdpi.com/1999-4923/13/7/949

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