Rheumatoid arthritis and pseudo-vesicular skin plaques: rheumatoid neutrophilic dermatosis

Abstract: A 54 year-old woman with a 3-year history of rheumatoid arthritis (RA) consulted us because of weight loss, fever and skin eruption. On physical examination, erythematous plaques with a pseudo-vesicular appearance were seen on the back of both shoulders. Histological examination was consis...

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Main Authors: Juan Manriquez, Laura Giesen, Constanza del Puerto, Sergio Gonzalez
Format: Article
Language:English
Published: Sociedade Brasileira de Dermatologia 2016-08-01
Series:Anais Brasileiros de Dermatologia
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016000400500&tlng=en
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author Juan Manriquez
Laura Giesen
Constanza del Puerto
Sergio Gonzalez
author_facet Juan Manriquez
Laura Giesen
Constanza del Puerto
Sergio Gonzalez
author_sort Juan Manriquez
collection DOAJ
description Abstract: A 54 year-old woman with a 3-year history of rheumatoid arthritis (RA) consulted us because of weight loss, fever and skin eruption. On physical examination, erythematous plaques with a pseudo-vesicular appearance were seen on the back of both shoulders. Histological examination was consistent with rheumatoid neutrophilic dermatosis (RND). After 3 days of prednisone treatment, the skin eruption resolved. RND is a rare cutaneous manifestation of seropositive RA, characterized by asymptomatic, symmetrical erythematous plaques with a pseudo-vesicular appearance. Histology characteristically reveals a dense, neutrophilic infiltrate with leucocitoclasis but without other signs of vasculitis. Lesions may resolve spontaneously or with RA treatment. This case illustrates an uncommon skin manifestation of active rheumatoid arthritis.
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spelling doaj.art-85dd56b3139b4936bc2bf742be90a42e2022-12-21T19:28:46ZengSociedade Brasileira de DermatologiaAnais Brasileiros de Dermatologia0365-05962016-08-0191450050210.1590/abd1806-4841.20164104Rheumatoid arthritis and pseudo-vesicular skin plaques: rheumatoid neutrophilic dermatosisJuan ManriquezLaura GiesenConstanza del PuertoSergio GonzalezAbstract: A 54 year-old woman with a 3-year history of rheumatoid arthritis (RA) consulted us because of weight loss, fever and skin eruption. On physical examination, erythematous plaques with a pseudo-vesicular appearance were seen on the back of both shoulders. Histological examination was consistent with rheumatoid neutrophilic dermatosis (RND). After 3 days of prednisone treatment, the skin eruption resolved. RND is a rare cutaneous manifestation of seropositive RA, characterized by asymptomatic, symmetrical erythematous plaques with a pseudo-vesicular appearance. Histology characteristically reveals a dense, neutrophilic infiltrate with leucocitoclasis but without other signs of vasculitis. Lesions may resolve spontaneously or with RA treatment. This case illustrates an uncommon skin manifestation of active rheumatoid arthritis.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016000400500&tlng=enArthritisArthritis, rheumatoidRheumatoid factor
spellingShingle Juan Manriquez
Laura Giesen
Constanza del Puerto
Sergio Gonzalez
Rheumatoid arthritis and pseudo-vesicular skin plaques: rheumatoid neutrophilic dermatosis
Anais Brasileiros de Dermatologia
Arthritis
Arthritis, rheumatoid
Rheumatoid factor
title Rheumatoid arthritis and pseudo-vesicular skin plaques: rheumatoid neutrophilic dermatosis
title_full Rheumatoid arthritis and pseudo-vesicular skin plaques: rheumatoid neutrophilic dermatosis
title_fullStr Rheumatoid arthritis and pseudo-vesicular skin plaques: rheumatoid neutrophilic dermatosis
title_full_unstemmed Rheumatoid arthritis and pseudo-vesicular skin plaques: rheumatoid neutrophilic dermatosis
title_short Rheumatoid arthritis and pseudo-vesicular skin plaques: rheumatoid neutrophilic dermatosis
title_sort rheumatoid arthritis and pseudo vesicular skin plaques rheumatoid neutrophilic dermatosis
topic Arthritis
Arthritis, rheumatoid
Rheumatoid factor
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016000400500&tlng=en
work_keys_str_mv AT juanmanriquez rheumatoidarthritisandpseudovesicularskinplaquesrheumatoidneutrophilicdermatosis
AT lauragiesen rheumatoidarthritisandpseudovesicularskinplaquesrheumatoidneutrophilicdermatosis
AT constanzadelpuerto rheumatoidarthritisandpseudovesicularskinplaquesrheumatoidneutrophilicdermatosis
AT sergiogonzalez rheumatoidarthritisandpseudovesicularskinplaquesrheumatoidneutrophilicdermatosis