The biology of bone morphogenetic protein signaling pathway in cerebrovascular system
Abstract Bone morphogenetic protein belongs to transcription growth factor superfamily β; bone morphogenetic protein signal pathway regulates cell proliferation, differentiation, and apoptosis among different tissues. Cerebrovascular system supplies sufficient oxygen and blood into brain to maintain...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2021-09-01
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| Series: | Chinese Neurosurgical Journal |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s41016-021-00254-0 |
| _version_ | 1819007664700522496 |
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| author | Haishuang Tang Xiaoxi Zhang Gaici Xue Fengfeng Xu Qingsong Wang Pengfei Yang Bo Hong Yi Xu Qinghai Huang Jianmin Liu Qiao Zuo |
| author_facet | Haishuang Tang Xiaoxi Zhang Gaici Xue Fengfeng Xu Qingsong Wang Pengfei Yang Bo Hong Yi Xu Qinghai Huang Jianmin Liu Qiao Zuo |
| author_sort | Haishuang Tang |
| collection | DOAJ |
| description | Abstract Bone morphogenetic protein belongs to transcription growth factor superfamily β; bone morphogenetic protein signal pathway regulates cell proliferation, differentiation, and apoptosis among different tissues. Cerebrovascular system supplies sufficient oxygen and blood into brain to maintain its normal function. The disorder of cerebrovascular system will result into serious cerebrovascular diseases, which is gradually becoming a major threat to human health in modern society. In recent decades, many studies have revealed the underlying biology and mechanism of bone morphogenetic protein signal pathway played in cerebrovascular system. This review will discuss the relationship between the two aspects, aiming to provide new perspective for non-invasive treatment and basic research of cerebrovascular diseases. |
| first_indexed | 2024-12-21T00:28:11Z |
| format | Article |
| id | doaj.art-85dfcf54e1534087974867e48fc0937d |
| institution | Directory Open Access Journal |
| issn | 2057-4967 |
| language | English |
| last_indexed | 2024-12-21T00:28:11Z |
| publishDate | 2021-09-01 |
| publisher | BMC |
| record_format | Article |
| series | Chinese Neurosurgical Journal |
| spelling | doaj.art-85dfcf54e1534087974867e48fc0937d2022-12-21T19:21:56ZengBMCChinese Neurosurgical Journal2057-49672021-09-01711810.1186/s41016-021-00254-0The biology of bone morphogenetic protein signaling pathway in cerebrovascular systemHaishuang Tang0Xiaoxi Zhang1Gaici Xue2Fengfeng Xu3Qingsong Wang4Pengfei Yang5Bo Hong6Yi Xu7Qinghai Huang8Jianmin Liu9Qiao Zuo10Department of Neurosurgery, Changhai Hospital, Naval Military Medical UniversityDepartment of Neurosurgery, Changhai Hospital, Naval Military Medical UniversityDepartment of Neurosurgery, Changhai Hospital, Naval Military Medical UniversityNaval Medical Center of PLA, Naval Military Medical UniversityDepartment of Cardiology, the First Medical Centre, Chinese PLA General HospitalDepartment of Neurosurgery, Changhai Hospital, Naval Military Medical UniversityDepartment of Neurosurgery, Changhai Hospital, Naval Military Medical UniversityDepartment of Neurosurgery, Changhai Hospital, Naval Military Medical UniversityDepartment of Neurosurgery, Changhai Hospital, Naval Military Medical UniversityDepartment of Neurosurgery, Changhai Hospital, Naval Military Medical UniversityDepartment of Neurosurgery, Changhai Hospital, Naval Military Medical UniversityAbstract Bone morphogenetic protein belongs to transcription growth factor superfamily β; bone morphogenetic protein signal pathway regulates cell proliferation, differentiation, and apoptosis among different tissues. Cerebrovascular system supplies sufficient oxygen and blood into brain to maintain its normal function. The disorder of cerebrovascular system will result into serious cerebrovascular diseases, which is gradually becoming a major threat to human health in modern society. In recent decades, many studies have revealed the underlying biology and mechanism of bone morphogenetic protein signal pathway played in cerebrovascular system. This review will discuss the relationship between the two aspects, aiming to provide new perspective for non-invasive treatment and basic research of cerebrovascular diseases.https://doi.org/10.1186/s41016-021-00254-0Bone morphogenetic proteinHemodynamicNeovascularizationCerebrovascular diseases |
| spellingShingle | Haishuang Tang Xiaoxi Zhang Gaici Xue Fengfeng Xu Qingsong Wang Pengfei Yang Bo Hong Yi Xu Qinghai Huang Jianmin Liu Qiao Zuo The biology of bone morphogenetic protein signaling pathway in cerebrovascular system Chinese Neurosurgical Journal Bone morphogenetic protein Hemodynamic Neovascularization Cerebrovascular diseases |
| title | The biology of bone morphogenetic protein signaling pathway in cerebrovascular system |
| title_full | The biology of bone morphogenetic protein signaling pathway in cerebrovascular system |
| title_fullStr | The biology of bone morphogenetic protein signaling pathway in cerebrovascular system |
| title_full_unstemmed | The biology of bone morphogenetic protein signaling pathway in cerebrovascular system |
| title_short | The biology of bone morphogenetic protein signaling pathway in cerebrovascular system |
| title_sort | biology of bone morphogenetic protein signaling pathway in cerebrovascular system |
| topic | Bone morphogenetic protein Hemodynamic Neovascularization Cerebrovascular diseases |
| url | https://doi.org/10.1186/s41016-021-00254-0 |
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