Biological and Computational Studies for Dual Cholinesterases Inhibitory Effect of Zerumbone

Biological and Computational Studies for Dual Cholinesterases Inhibitory Effect of Zerumbone

Acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) mediate the degradation of acetylcholine (ACh), a primary neurotransmitter in the brain. Cholinergic deficiency occurs during the progression of Alzheimer’s disease (AD), resulting in widespread cognitive dysfunction and decline. We evalua...

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Bibliographic Details
Main Authors:	Jayeong Hwang, Kumju Youn, Yeongseon Ji, Seonah Lee, Gyutae Lim, Jinhyuk Lee, Chi-Tang Ho, Sun-Hee Leem, Mira Jun
Format:	Article
Language:	English
Published:	MDPI AG 2020-04-01
Series:	Nutrients
Subjects:	ADMET Alzheimer’s disease (AD) cholinesterases computational docking simulation zerumbone
Online Access:	https://www.mdpi.com/2072-6643/12/5/1215

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