Power signatures of habenular neuronal signals in patients with bipolar or unipolar depressive disorders correlate with their disease severity
Abstract The habenula is an epithalamic structure implicated in negative reward mechanisms and plays a downstream modulatory role in regulation of dopaminergic and serotonergic functions. Human and animal studies show its hyperactivity in depression which is curtailed by the antidepressant response...
Main Authors: | Saurabh Sonkusare, Qiong Ding, Yingying Zhang, Linbin Wang, Hengfen Gong, Alekhya Mandali, Luis Manssuer, Yi-Jie Zhao, Yixin Pan, Chencheng Zhang, Dianyou Li, Bomin Sun, Valerie Voon |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2022-02-01
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Series: | Translational Psychiatry |
Online Access: | https://doi.org/10.1038/s41398-022-01830-3 |
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