Near infrared photoimmunotherapy of cancer; possible clinical applications

Near infrared photoimmunotherapy of cancer; possible clinical applications

Near-infrared photoimmunotherapy (NIR-PIT) is a new cancer treatment that uses an antibody-photo-absorber conjugate (APC) composed of a targeting monoclonal antibody conjugated with a photoactivatable phthalocyanine-derivative dye, IRDye700DX (IR700). APCs injected into the body can bind to cancer c...

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Bibliographic Details
Main Authors:	Wakiyama Hiroaki, Kato Takuya, Furusawa Aki, Choyke Peter L., Kobayashi Hisataka
Format:	Article
Language:	English
Published:	De Gruyter 2021-05-01
Series:	Nanophotonics
Subjects:	anti-cancer host immunity cancer immunogenic cell death near-infrared photoimmunotherapy (nir-pit) super-enhanced permeability and retention (supr) effects
Online Access:	https://doi.org/10.1515/nanoph-2021-0119

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