Blockade of CXCR1/2 chemokine receptors protects against brain damage in ischemic stroke in mice

Blockade of CXCR1/2 chemokine receptors protects against brain damage in ischemic stroke in mice

OBJECTIVE: Ischemic stroke may result from transient or permanent reductions of regional cerebral blood flow. Polymorphonuclear neutrophils have been described as the earliest inflammatory cells to arrive in ischemic tissue. CXCR1/2 receptors are involved in the recruitment of these cells. However,...

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Bibliographic Details
Main Authors: Larissa Fonseca da Cunha Sousa, Fernanda Matos Coelho, David Henrique Rodrigues, Alline Cristina Campos, Luciola da Silva Barcelos, Mauro Martins Teixeira, Milene Alvarenga Rachid, Antonio Lucio Teixeira
Format: Article
Language:English
Published: Elsevier España 2013-01-01
Series:Clinics
Subjects:
Cerebral Ischemia
Neutrophils
Reparixin
CXCR1/CXCR2 Receptors
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322013000300018

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