Malaria and curable sexually transmitted and reproductive tract coinfection among pregnant women in rural Burkina Faso
Abstract Background Malaria and sexually transmitted/reproductive tract infections (STI/RTI) are leading and preventable causes of low birthweight in sub-Saharan Africa. Reducing their impact on pregnancy outcomes requires efficient interventions that can be easily integrated into the antenatal care...
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| Format: | Article |
| Language: | English |
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BMC
2021-11-01
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| Series: | Tropical Medicine and Health |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s41182-021-00381-5 |
| _version_ | 1819008712646328320 |
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| author | Moussa Lingani Serge H. Zango Innocent Valéa Massa dit A. Bonko Sékou O. Samadoulougou Toussaint Rouamba Marc C. Tahita Maïmouna Sanou Annie Robert Halidou Tinto Philippe Donnen Michèle Dramaix |
| author_facet | Moussa Lingani Serge H. Zango Innocent Valéa Massa dit A. Bonko Sékou O. Samadoulougou Toussaint Rouamba Marc C. Tahita Maïmouna Sanou Annie Robert Halidou Tinto Philippe Donnen Michèle Dramaix |
| author_sort | Moussa Lingani |
| collection | DOAJ |
| description | Abstract Background Malaria and sexually transmitted/reproductive tract infections (STI/RTI) are leading and preventable causes of low birthweight in sub-Saharan Africa. Reducing their impact on pregnancy outcomes requires efficient interventions that can be easily integrated into the antenatal care package. The paucity of data on malaria and STI/RTI coinfection, however, limits efforts to control these infections. This study aimed to determine the prevalence and associated factors of malaria and STI/RTI coinfection among pregnant women in rural Burkina Faso. Methods A cross-sectional survey was conducted among 402 pregnant women attending antenatal clinics at the Yako health district. Sociodemographic and behavioral data were collected, and pregnant women were tested for peripheral malaria by microscopy. Hemoglobin levels were also measured by spectrophotometry and curable bacterial STI/RTI were tested on cervico-vaginal swabs using rapid diagnostic test for chlamydia and syphilis, and Gram staining for bacterial vaginosis. A multivariate logistic regression model was used to assess the association of malaria and STI/RTI coinfection with the characteristics of included pregnant women. Results The prevalence of malaria and at least one STI/RTI coinfection was 12.9% (95% confidence interval, CI: [9.8–16.7]), malaria and bacterial vaginosis coinfection was 12.2% (95% CI: [9.3–15.9]), malaria and chlamydial coinfection was 1.6% (95% CI: [0.6–3.8]). No coinfection was reported for malaria and syphilis. The individual prevalence was 17.2%, 7.2%, 0.6%, 67.7% and 73.3%, respectively, for malaria infection, chlamydia, syphilis, bacterial vaginosis and STI/RTI combination. Only 10% of coinfections were symptomatic, and thus, 90% of women with coinfection would have been missed by the symptoms-based diagnostic approach. In the multivariate analysis, the first pregnancy (aOR = 2.4 [95% CI: 1.2–4.7]) was the only factor significantly associated with malaria and STI/RTI coinfection. Clinical symptoms were not associated with malaria and STI/RTI coinfection. Conclusion The prevalence of malaria and curable STI/RTI coinfection was high among pregnant women. The poor performance of the clinical symptoms to predict coinfection suggests that alternative interventions are needed. |
| first_indexed | 2024-12-21T00:44:50Z |
| format | Article |
| id | doaj.art-85e925164d904dc9bee09972b7d0c296 |
| institution | Directory Open Access Journal |
| issn | 1349-4147 |
| language | English |
| last_indexed | 2024-12-21T00:44:50Z |
| publishDate | 2021-11-01 |
| publisher | BMC |
| record_format | Article |
| series | Tropical Medicine and Health |
| spelling | doaj.art-85e925164d904dc9bee09972b7d0c2962022-12-21T19:21:33ZengBMCTropical Medicine and Health1349-41472021-11-014911910.1186/s41182-021-00381-5Malaria and curable sexually transmitted and reproductive tract coinfection among pregnant women in rural Burkina FasoMoussa Lingani0Serge H. Zango1Innocent Valéa2Massa dit A. Bonko3Sékou O. Samadoulougou4Toussaint Rouamba5Marc C. Tahita6Maïmouna Sanou7Annie Robert8Halidou Tinto9Philippe Donnen10Michèle Dramaix11École de Santé Publique, Université Libre de BruxellesInstitut de Recherche en Sciences de la Santé/Direction Régionale du Centre Ouest (IRSS/DRCO)Institut de Recherche en Sciences de la Santé/Direction Régionale du Centre Ouest (IRSS/DRCO)Institut de Recherche en Sciences de la Santé/Direction Régionale du Centre Ouest (IRSS/DRCO)Evaluation Platform On Obesity Prevention, Quebec Heart and Lung Institute Research CenterInstitut de Recherche en Sciences de la Santé/Direction Régionale du Centre Ouest (IRSS/DRCO)Institut de Recherche en Sciences de la Santé/Direction Régionale du Centre Ouest (IRSS/DRCO)Institut de Recherche en Sciences de la Santé/Direction Régionale du Centre Ouest (IRSS/DRCO)Epidemiology and Biostatistics Research Division, Institut de Recherche Expérimentale et Clinique, Université Catholique de LouvainInstitut de Recherche en Sciences de la Santé/Direction Régionale du Centre Ouest (IRSS/DRCO)École de Santé Publique, Université Libre de BruxellesÉcole de Santé Publique, Université Libre de BruxellesAbstract Background Malaria and sexually transmitted/reproductive tract infections (STI/RTI) are leading and preventable causes of low birthweight in sub-Saharan Africa. Reducing their impact on pregnancy outcomes requires efficient interventions that can be easily integrated into the antenatal care package. The paucity of data on malaria and STI/RTI coinfection, however, limits efforts to control these infections. This study aimed to determine the prevalence and associated factors of malaria and STI/RTI coinfection among pregnant women in rural Burkina Faso. Methods A cross-sectional survey was conducted among 402 pregnant women attending antenatal clinics at the Yako health district. Sociodemographic and behavioral data were collected, and pregnant women were tested for peripheral malaria by microscopy. Hemoglobin levels were also measured by spectrophotometry and curable bacterial STI/RTI were tested on cervico-vaginal swabs using rapid diagnostic test for chlamydia and syphilis, and Gram staining for bacterial vaginosis. A multivariate logistic regression model was used to assess the association of malaria and STI/RTI coinfection with the characteristics of included pregnant women. Results The prevalence of malaria and at least one STI/RTI coinfection was 12.9% (95% confidence interval, CI: [9.8–16.7]), malaria and bacterial vaginosis coinfection was 12.2% (95% CI: [9.3–15.9]), malaria and chlamydial coinfection was 1.6% (95% CI: [0.6–3.8]). No coinfection was reported for malaria and syphilis. The individual prevalence was 17.2%, 7.2%, 0.6%, 67.7% and 73.3%, respectively, for malaria infection, chlamydia, syphilis, bacterial vaginosis and STI/RTI combination. Only 10% of coinfections were symptomatic, and thus, 90% of women with coinfection would have been missed by the symptoms-based diagnostic approach. In the multivariate analysis, the first pregnancy (aOR = 2.4 [95% CI: 1.2–4.7]) was the only factor significantly associated with malaria and STI/RTI coinfection. Clinical symptoms were not associated with malaria and STI/RTI coinfection. Conclusion The prevalence of malaria and curable STI/RTI coinfection was high among pregnant women. The poor performance of the clinical symptoms to predict coinfection suggests that alternative interventions are needed.https://doi.org/10.1186/s41182-021-00381-5PregnancyMalariaSyphilisChlamydiaBacterial vaginosisCoinfection |
| spellingShingle | Moussa Lingani Serge H. Zango Innocent Valéa Massa dit A. Bonko Sékou O. Samadoulougou Toussaint Rouamba Marc C. Tahita Maïmouna Sanou Annie Robert Halidou Tinto Philippe Donnen Michèle Dramaix Malaria and curable sexually transmitted and reproductive tract coinfection among pregnant women in rural Burkina Faso Tropical Medicine and Health Pregnancy Malaria Syphilis Chlamydia Bacterial vaginosis Coinfection |
| title | Malaria and curable sexually transmitted and reproductive tract coinfection among pregnant women in rural Burkina Faso |
| title_full | Malaria and curable sexually transmitted and reproductive tract coinfection among pregnant women in rural Burkina Faso |
| title_fullStr | Malaria and curable sexually transmitted and reproductive tract coinfection among pregnant women in rural Burkina Faso |
| title_full_unstemmed | Malaria and curable sexually transmitted and reproductive tract coinfection among pregnant women in rural Burkina Faso |
| title_short | Malaria and curable sexually transmitted and reproductive tract coinfection among pregnant women in rural Burkina Faso |
| title_sort | malaria and curable sexually transmitted and reproductive tract coinfection among pregnant women in rural burkina faso |
| topic | Pregnancy Malaria Syphilis Chlamydia Bacterial vaginosis Coinfection |
| url | https://doi.org/10.1186/s41182-021-00381-5 |
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