Generalized Severe Plaque Psoriasis in an HIV Positive Patient – a Challenging Treatment

Psoriasis is a systemic chronic immune-mediated disorder, rarely reported in HIV-infected patients, in which the disease is more severe and debilitating. Response to treatment is modest, and skin diseases may profoundly affect the patients’ quality of life. Anti-psoriasis therapies have immunosuppre...

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Main Authors: Chiriac Anca, Georgescu Rareș, Brzezinski Piotr, Stolnicu Simona
Format: Article
Language:English
Published: Sciendo 2017-03-01
Series:Journal of Interdisciplinary Medicine
Subjects:
Online Access:http://www.degruyter.com/view/j/jim.2017.2.issue-1/jim-2017-0029/jim-2017-0029.xml?format=INT
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author Chiriac Anca
Georgescu Rareș
Brzezinski Piotr
Stolnicu Simona
author_facet Chiriac Anca
Georgescu Rareș
Brzezinski Piotr
Stolnicu Simona
author_sort Chiriac Anca
collection DOAJ
description Psoriasis is a systemic chronic immune-mediated disorder, rarely reported in HIV-infected patients, in which the disease is more severe and debilitating. Response to treatment is modest, and skin diseases may profoundly affect the patients’ quality of life. Anti-psoriasis therapies have immunosuppressive effects and must be carefully recommended in HIV-infected patients. Moreover, the compliance of HIV patients diagnosed with psoriasis is low, and monitoring these patients is challenging. Herein we present a rare case of severe HIV-associated psoriasis with large plaques localized on the trunk, abdomen, limbs and plantar area in a non-compliant patient, with impaired renal and hepatic functions, dyslipidemia, and anemia, for whom the therapeutic approach was disappointing.
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spelling doaj.art-85ea5c7a8d7b4609a9cd94f1e99ee4292022-12-22T02:22:32ZengSciendoJournal of Interdisciplinary Medicine2501-81322017-03-0121777910.1515/jim-2017-0029jim-2017-0029Generalized Severe Plaque Psoriasis in an HIV Positive Patient – a Challenging TreatmentChiriac Anca0Georgescu Rareș1Brzezinski Piotr2Stolnicu Simona3Apollonia University, Department of Dermato-Physiology, Iași, RomaniaDepartment of Surgery, University of Medicine and Pharmacy, Tîrgu Mureș, RomaniaDepartment of Dermatology, 6th Military Support Unit, Ustka, PolandDepartment of Pathology, University of Medicine and Pharmacy, Tîrgu Mureș, RomaniaPsoriasis is a systemic chronic immune-mediated disorder, rarely reported in HIV-infected patients, in which the disease is more severe and debilitating. Response to treatment is modest, and skin diseases may profoundly affect the patients’ quality of life. Anti-psoriasis therapies have immunosuppressive effects and must be carefully recommended in HIV-infected patients. Moreover, the compliance of HIV patients diagnosed with psoriasis is low, and monitoring these patients is challenging. Herein we present a rare case of severe HIV-associated psoriasis with large plaques localized on the trunk, abdomen, limbs and plantar area in a non-compliant patient, with impaired renal and hepatic functions, dyslipidemia, and anemia, for whom the therapeutic approach was disappointing.http://www.degruyter.com/view/j/jim.2017.2.issue-1/jim-2017-0029/jim-2017-0029.xml?format=INThuman immunodeficiency virus (HIV)psoriasis
spellingShingle Chiriac Anca
Georgescu Rareș
Brzezinski Piotr
Stolnicu Simona
Generalized Severe Plaque Psoriasis in an HIV Positive Patient – a Challenging Treatment
Journal of Interdisciplinary Medicine
human immunodeficiency virus (HIV)
psoriasis
title Generalized Severe Plaque Psoriasis in an HIV Positive Patient – a Challenging Treatment
title_full Generalized Severe Plaque Psoriasis in an HIV Positive Patient – a Challenging Treatment
title_fullStr Generalized Severe Plaque Psoriasis in an HIV Positive Patient – a Challenging Treatment
title_full_unstemmed Generalized Severe Plaque Psoriasis in an HIV Positive Patient – a Challenging Treatment
title_short Generalized Severe Plaque Psoriasis in an HIV Positive Patient – a Challenging Treatment
title_sort generalized severe plaque psoriasis in an hiv positive patient a challenging treatment
topic human immunodeficiency virus (HIV)
psoriasis
url http://www.degruyter.com/view/j/jim.2017.2.issue-1/jim-2017-0029/jim-2017-0029.xml?format=INT
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AT georgescurares generalizedsevereplaquepsoriasisinanhivpositivepatientachallengingtreatment
AT brzezinskipiotr generalizedsevereplaquepsoriasisinanhivpositivepatientachallengingtreatment
AT stolnicusimona generalizedsevereplaquepsoriasisinanhivpositivepatientachallengingtreatment