Peptides in Dentistry: A Scoping Review
Currently, it remains unclear which specific peptides could be appropriate for applications in different fields of dentistry. The aim of this scoping review was to scan the contemporary scientific papers related to the types, uses and applications of peptides in dentistry at the moment. Literature d...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-02-01
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| Series: | Bioengineering |
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| Online Access: | https://www.mdpi.com/2306-5354/10/2/214 |
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| author | Louis Hardan Jean Claude Abou Chedid Rim Bourgi Carlos Enrique Cuevas-Suárez Monika Lukomska-Szymanska Vincenzo Tosco Ana Josefina Monjarás-Ávila Massa Jabra Fouad Salloum-Yared Naji Kharouf Davide Mancino Youssef Haikel |
| author_facet | Louis Hardan Jean Claude Abou Chedid Rim Bourgi Carlos Enrique Cuevas-Suárez Monika Lukomska-Szymanska Vincenzo Tosco Ana Josefina Monjarás-Ávila Massa Jabra Fouad Salloum-Yared Naji Kharouf Davide Mancino Youssef Haikel |
| author_sort | Louis Hardan |
| collection | DOAJ |
| description | Currently, it remains unclear which specific peptides could be appropriate for applications in different fields of dentistry. The aim of this scoping review was to scan the contemporary scientific papers related to the types, uses and applications of peptides in dentistry at the moment. Literature database searches were performed in the following databases: PubMed/MEDLINE, Scopus, Web of Science, Embase, and Scielo. A total of 133 articles involving the use of peptides in dentistry-related applications were included. The studies involved experimental designs in animals, microorganisms, or cells; clinical trials were also identified within this review. Most of the applications of peptides included caries management, implant osseointegration, guided tissue regeneration, vital pulp therapy, antimicrobial activity, enamel remineralization, periodontal therapy, the surface modification of tooth implants, and the modification of other restorative materials such as dental adhesives and denture base resins. The in vitro and in vivo studies included in this review suggested that peptides may have beneficial effects for treating early carious lesions, promoting cell adhesion, enhancing the adhesion strength of dental implants, and in tissue engineering as healthy promotors of the periodontium and antimicrobial agents. The lack of clinical trials should be highlighted, leaving a wide space available for the investigation of peptides in dentistry. |
| first_indexed | 2024-03-11T09:09:08Z |
| format | Article |
| id | doaj.art-85eb947a03d045f6965cd7250161da1b |
| institution | Directory Open Access Journal |
| issn | 2306-5354 |
| language | English |
| last_indexed | 2024-03-11T09:09:08Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Bioengineering |
| spelling | doaj.art-85eb947a03d045f6965cd7250161da1b2023-11-16T19:11:16ZengMDPI AGBioengineering2306-53542023-02-0110221410.3390/bioengineering10020214Peptides in Dentistry: A Scoping ReviewLouis Hardan0Jean Claude Abou Chedid1Rim Bourgi2Carlos Enrique Cuevas-Suárez3Monika Lukomska-Szymanska4Vincenzo Tosco5Ana Josefina Monjarás-Ávila6Massa Jabra7Fouad Salloum-Yared8Naji Kharouf9Davide Mancino10Youssef Haikel11Department of Restorative Dentistry, School of Dentistry, Saint Joseph University, Beirut 1107 2180, LebanonDepartment of Pediatric Dentistry, Faculty of Dentistry, Saint Joseph University, Beirut 1107 2180, LebanonDepartment of Restorative Dentistry, School of Dentistry, Saint Joseph University, Beirut 1107 2180, LebanonDental Materials Laboratory, Academic Area of Dentistry, Autonomous University of Hidalgo State, San Agustín Tlaxiaca 42160, MexicoDepartment of General Dentistry, Medical University of Lodz, 251 Pomorska St., 92-213 Lodz, PolandDepartment of Clinical Sciences and Stomatology (DISCO), Polytechnic University of Marche, 60126 Ancona, ItalyDental Materials Laboratory, Academic Area of Dentistry, Autonomous University of Hidalgo State, San Agustín Tlaxiaca 42160, MexicoFaculty of Medicine, Damascus University, Damascus 0100, SyriaPrivate Practice, 54290 Trier, GermanyDepartment of Biomaterials and Bioengineering, INSERM UMR_S 1121, University of Strasbourg, 67000 Strasbourg, FranceDepartment of Biomaterials and Bioengineering, INSERM UMR_S 1121, University of Strasbourg, 67000 Strasbourg, FranceDepartment of Biomaterials and Bioengineering, INSERM UMR_S 1121, University of Strasbourg, 67000 Strasbourg, FranceCurrently, it remains unclear which specific peptides could be appropriate for applications in different fields of dentistry. The aim of this scoping review was to scan the contemporary scientific papers related to the types, uses and applications of peptides in dentistry at the moment. Literature database searches were performed in the following databases: PubMed/MEDLINE, Scopus, Web of Science, Embase, and Scielo. A total of 133 articles involving the use of peptides in dentistry-related applications were included. The studies involved experimental designs in animals, microorganisms, or cells; clinical trials were also identified within this review. Most of the applications of peptides included caries management, implant osseointegration, guided tissue regeneration, vital pulp therapy, antimicrobial activity, enamel remineralization, periodontal therapy, the surface modification of tooth implants, and the modification of other restorative materials such as dental adhesives and denture base resins. The in vitro and in vivo studies included in this review suggested that peptides may have beneficial effects for treating early carious lesions, promoting cell adhesion, enhancing the adhesion strength of dental implants, and in tissue engineering as healthy promotors of the periodontium and antimicrobial agents. The lack of clinical trials should be highlighted, leaving a wide space available for the investigation of peptides in dentistry.https://www.mdpi.com/2306-5354/10/2/214antimicrobialosseointegrationsurface modificationtissue engineering |
| spellingShingle | Louis Hardan Jean Claude Abou Chedid Rim Bourgi Carlos Enrique Cuevas-Suárez Monika Lukomska-Szymanska Vincenzo Tosco Ana Josefina Monjarás-Ávila Massa Jabra Fouad Salloum-Yared Naji Kharouf Davide Mancino Youssef Haikel Peptides in Dentistry: A Scoping Review Bioengineering antimicrobial osseointegration surface modification tissue engineering |
| title | Peptides in Dentistry: A Scoping Review |
| title_full | Peptides in Dentistry: A Scoping Review |
| title_fullStr | Peptides in Dentistry: A Scoping Review |
| title_full_unstemmed | Peptides in Dentistry: A Scoping Review |
| title_short | Peptides in Dentistry: A Scoping Review |
| title_sort | peptides in dentistry a scoping review |
| topic | antimicrobial osseointegration surface modification tissue engineering |
| url | https://www.mdpi.com/2306-5354/10/2/214 |
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