First report of the blaOXA-58 gene in a clinical isolate of Acinetobacter baumannii in Rio de Janeiro, Brazil

First report of the blaOXA-58 gene in a clinical isolate of Acinetobacter baumannii in Rio de Janeiro, Brazil

Carbapenemase production is an important mechanism of carbapenem resistance among nonfermentative Gram-negative isolates. This study aimed to report the detection of blaOXA-58 gene in multiresistant clinical isolates of Acinetobacter baumannii recovered from inpatients in a public hospital. Polymera...

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Bibliographic Details
Main Authors: Deuseli Quaresma de Figueiredo, Kátia Regina Netto dos Santos, Eliezer Menezes Pereira, Ricardo Pinto Schuenck, Cláudia Rezende Vieira de Mendonça-Souza, Lúcia Martins Teixeira, Silvia Susana Bona de Mondino
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2011-05-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
Acinetobacter baumannii
oxacillinases
OXA-58
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762011000300019&lng=en&tlng=en
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Summary:Carbapenemase production is an important mechanism of carbapenem resistance among nonfermentative Gram-negative isolates. This study aimed to report the detection of blaOXA-58 gene in multiresistant clinical isolates of Acinetobacter baumannii recovered from inpatients in a public hospital. Polymerase chain reaction tests were performed to detect the blaOXA-23-like, blaOXA-24-like, blaOXA-58-like and blaOXA-51-like genes. The blaOXA-58 and blaOXA-23 genes were detected in one and three isolates, respectively. Sequencing of the blaOXA-58-like amplicon revealed 100% identity with the A. baumannii blaOXA-58 gene listed in the GenBank database. This is the first report of an OXA-58-producing A. baumannii isolate in Rio de Janeiro, Brazil.
ISSN:1678-8060

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