Challenges of correlating pH change with relief of clinical symptoms in gastro esophageal reflux disease: a phase III, randomized study of Zegerid versus Losec.

Challenges of correlating pH change with relief of clinical symptoms in gastro esophageal reflux disease: a phase III, randomized study of Zegerid versus Losec.

<h4>Background</h4>Zegerid (on demand immediate-release omeprazole and sodium bicarbonate combination therapy) has demonstrated earlier absorption and more rapid pH change compared with Losec (standard enteric coated omeprazole), suggesting more rapid clinical relief of heartburn. This P...

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Bibliographic Details
Main Authors: Dave Walker, Richard Ng Kwet Shing, Deborah Jones, Hans-Jurgen Gruss, Jarosław Reguła
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0116308&type=printable

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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0116308&type=printable

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