Structural mechanism of intracellular autoregulation of zinc uptake in ZIP transporters
Abstract Zinc is an essential micronutrient that supports all living organisms through regulating numerous biological processes. However, the mechanism of uptake regulation by intracellular Zn2+ status remains unclear. Here we report a cryo-electron microscopy structure of a ZIP-family transporter f...
Main Authors: | Changxu Pang, Jin Chai, Ping Zhu, John Shanklin, Qun Liu |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-06-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-023-39010-6 |
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