Engineered exosomes enriched with select microRNAs amplify their therapeutic efficacy for traumatic brain injury and stroke

Engineered exosomes enriched with select microRNAs amplify their therapeutic efficacy for traumatic brain injury and stroke

Traumatic brain injury (TBI) and stroke stand as prominent causes of global disability and mortality. Treatment strategies for stroke and TBI are shifting from targeting neuroprotection toward cell-based neurorestorative strategy, aiming to augment endogenous brain remodeling, which holds considerab...

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Bibliographic Details
Main Authors: Liang Chen, Ye Xiong, Michael Chopp, Yanlu Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Cellular Neuroscience
Subjects:
exosome
stroke
traumatic brain injury (TBI)
miRNA
engineered exosome
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2024.1376601/full

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