CD169-mediated restrictive SARS-CoV-2 infection of macrophages induces pro-inflammatory responses.
Exacerbated and persistent innate immune response marked by pro-inflammatory cytokine expression is thought to be a major driver of chronic COVID-19 pathology. Although macrophages are not the primary target cells of SARS-CoV-2 infection in humans, viral RNA and antigens in activated monocytes and m...
Main Authors: | Sallieu Jalloh, Judith Olejnik, Jacob Berrigan, Annuurun Nisa, Ellen L Suder, Hisashi Akiyama, Maohua Lei, Sita Ramaswamy, Sanjay Tyagi, Yuri Bushkin, Elke Mühlberger, Suryaram Gummuluru |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2022-10-01
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Series: | PLoS Pathogens |
Online Access: | https://doi.org/10.1371/journal.ppat.1010479 |
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