Biochemical and physiological effect of dietary supplements of ZnO nanoparticles on common carp (Cyprinus carpio)
ZnO-NPs, like other macromolecule sources, may provide the fish with sufficient amounts of zinc and be effective in regulating the biochemical function of cells in organisms. This study aimed to assess the possibility of using nanoparticles in common carp diet by evaluating alterations in blood bioc...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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University of Tehran
2019-02-01
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| Series: | International Journal of Aquatic Biology |
| Subjects: | |
| Online Access: | http://ij-aquaticbiology.com/index.php/ijab/article/view/590 |
| _version_ | 1818204322413936640 |
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| author | Mahdi Banaee Maryam Vaziriyan Azam Derikvandy Behzad Nematdoost Haghi Mohammad Mohiseni |
| author_facet | Mahdi Banaee Maryam Vaziriyan Azam Derikvandy Behzad Nematdoost Haghi Mohammad Mohiseni |
| author_sort | Mahdi Banaee |
| collection | DOAJ |
| description | ZnO-NPs, like other macromolecule sources, may provide the fish with sufficient amounts of zinc and be effective in regulating the biochemical function of cells in organisms. This study aimed to assess the possibility of using nanoparticles in common carp diet by evaluating alterations in blood biochemical parameters, as a clinical marker of fish health. In this study, fish were fed diets supplemented with 0 (control), 5, 10 and 15 mg kg-1 ZnO-NPs for 21 days. The results showed that after 21 days admiration of ZnO-NPs, 10 and 15 mg kg-1 concentrations significantly increased aspartate aminotransferase (AST) activity and glucose, cholesterol, triglyceride and creatinine levels in plasma of fish (P<0.05). Also, the administration of 15 mg kg-1 ZnO-NPs significantly (P<0.05) increased alanine aminotransferase (ALT), Lactate dehydrogenase (LDH) and alkaline phosphatase (ALP) activities. No significant changes were observed in plasma total protein, albumin and globulin levels (P>0.05). In conclusion, the results showed that diets containing high concentrations of ZnO-NPs supplement (10 and 15 mg) is caused severe cytotoxic effects, including changes in blood biochemical parameters. The primary toxic mechanism of ZnO-NPs was possibly increasing the cellular oxidative stress and disrupting the biochemical function of cells. |
| first_indexed | 2024-12-12T03:39:24Z |
| format | Article |
| id | doaj.art-85f9062a7ffc4979805ca0e30fa88d1e |
| institution | Directory Open Access Journal |
| issn | 2383-0956 2322-5270 |
| language | English |
| last_indexed | 2024-12-12T03:39:24Z |
| publishDate | 2019-02-01 |
| publisher | University of Tehran |
| record_format | Article |
| series | International Journal of Aquatic Biology |
| spelling | doaj.art-85f9062a7ffc4979805ca0e30fa88d1e2022-12-22T00:39:42ZengUniversity of TehranInternational Journal of Aquatic Biology2383-09562322-52702019-02-0171566410.22034/ijab.v7i1.590293Biochemical and physiological effect of dietary supplements of ZnO nanoparticles on common carp (Cyprinus carpio)Mahdi Banaee0Maryam Vaziriyan1Azam Derikvandy2Behzad Nematdoost Haghi3Mohammad Mohiseni4Aquaculture Department, Natural Resource Faculity, Behbahan Khatam Alanbia University of Technology, Behbahan, Iran.Aquaculture Department, Natural Resource Faculity, Behbahan Khatam Alanbia University of Technology, Behbahan, Iran.Department of Environment, Faculty of Natural Resources and Environment, Behbahan Khatam Alanbia University of Technology, Iran.Aquaculture Department, Faculty of Natural Resources and the Environment, Behbahan Khatam Alanbia University of Technology, Behbahan, Iran.Aquaculture Department, Faculty of Natural Resources and the Environment, Behbahan Khatam Alanbia University of Technology, Behbahan, Iran.ZnO-NPs, like other macromolecule sources, may provide the fish with sufficient amounts of zinc and be effective in regulating the biochemical function of cells in organisms. This study aimed to assess the possibility of using nanoparticles in common carp diet by evaluating alterations in blood biochemical parameters, as a clinical marker of fish health. In this study, fish were fed diets supplemented with 0 (control), 5, 10 and 15 mg kg-1 ZnO-NPs for 21 days. The results showed that after 21 days admiration of ZnO-NPs, 10 and 15 mg kg-1 concentrations significantly increased aspartate aminotransferase (AST) activity and glucose, cholesterol, triglyceride and creatinine levels in plasma of fish (P<0.05). Also, the administration of 15 mg kg-1 ZnO-NPs significantly (P<0.05) increased alanine aminotransferase (ALT), Lactate dehydrogenase (LDH) and alkaline phosphatase (ALP) activities. No significant changes were observed in plasma total protein, albumin and globulin levels (P>0.05). In conclusion, the results showed that diets containing high concentrations of ZnO-NPs supplement (10 and 15 mg) is caused severe cytotoxic effects, including changes in blood biochemical parameters. The primary toxic mechanism of ZnO-NPs was possibly increasing the cellular oxidative stress and disrupting the biochemical function of cells.http://ij-aquaticbiology.com/index.php/ijab/article/view/590common carp, dietary exposure, zno-nanoparticle, plasma. |
| spellingShingle | Mahdi Banaee Maryam Vaziriyan Azam Derikvandy Behzad Nematdoost Haghi Mohammad Mohiseni Biochemical and physiological effect of dietary supplements of ZnO nanoparticles on common carp (Cyprinus carpio) International Journal of Aquatic Biology common carp, dietary exposure, zno-nanoparticle, plasma. |
| title | Biochemical and physiological effect of dietary supplements of ZnO nanoparticles on common carp (Cyprinus carpio) |
| title_full | Biochemical and physiological effect of dietary supplements of ZnO nanoparticles on common carp (Cyprinus carpio) |
| title_fullStr | Biochemical and physiological effect of dietary supplements of ZnO nanoparticles on common carp (Cyprinus carpio) |
| title_full_unstemmed | Biochemical and physiological effect of dietary supplements of ZnO nanoparticles on common carp (Cyprinus carpio) |
| title_short | Biochemical and physiological effect of dietary supplements of ZnO nanoparticles on common carp (Cyprinus carpio) |
| title_sort | biochemical and physiological effect of dietary supplements of zno nanoparticles on common carp cyprinus carpio |
| topic | common carp, dietary exposure, zno-nanoparticle, plasma. |
| url | http://ij-aquaticbiology.com/index.php/ijab/article/view/590 |
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