Supporting clinical management of the difficult-to-treat TB cases: the ERS-WHO TB Consilium
Multi-drug and extensively drug-resistant tuberculosis (MDR/XDR-TB) are considered a serious threat for TB control and elimination. The outcome of these patients is still largely unsatisfactory as of today, with treatment success rates being consistently below 50% at global level. The World Health O...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2015-03-01
|
| Series: | International Journal of Infectious Diseases |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1201971214017421 |
| _version_ | 1819041046866165760 |
|---|---|
| author | Lia D’Ambrosio Marina Tadolini Rosella Centis Raquel Duarte Giovanni Sotgiu Stefano Aliberti Masoud Dara Giovanni Battista Migliori |
| author_facet | Lia D’Ambrosio Marina Tadolini Rosella Centis Raquel Duarte Giovanni Sotgiu Stefano Aliberti Masoud Dara Giovanni Battista Migliori |
| author_sort | Lia D’Ambrosio |
| collection | DOAJ |
| description | Multi-drug and extensively drug-resistant tuberculosis (MDR/XDR-TB) are considered a serious threat for TB control and elimination. The outcome of these patients is still largely unsatisfactory as of today, with treatment success rates being consistently below 50% at global level.
The World Health Organization (WHO) recommends that management of MDR-TB cases is supported by a specialized team, including complementary medical professionals able to cover several perspectives (clinical, both for adults and children; surgical; radiological; public health; psychological; nursing, among others). Implementation of such a body (known as Consilium in most of the former Soviet Union countries) is often a pre-requisite to apply for international TB control funding and concessionally priced medicines to treat M/XDR-TB cases.
The primary objective of the ERS/WHO TB Consilium is to provide clinical consultation for drug-resistant TB and other difficult-to-treat TB cases, including co-infection with HIV and paediatric cases. Through technical guidance to clinicians managing complex TB cases, the main contribution and outcome of the initiative will be a public health response aimed at achieving correct treatment of affected patients and preventing further development of drug resistance. The Consilum's secondary objective is to ensure monitoring and evaluation of clinical practices on the ground (diagnosis, treatment and prevention). |
| first_indexed | 2024-12-21T09:18:46Z |
| format | Article |
| id | doaj.art-85f98907e73045438a6cdd0fc0a2ee87 |
| institution | Directory Open Access Journal |
| issn | 1201-9712 1878-3511 |
| language | English |
| last_indexed | 2024-12-21T09:18:46Z |
| publishDate | 2015-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | International Journal of Infectious Diseases |
| spelling | doaj.art-85f98907e73045438a6cdd0fc0a2ee872022-12-21T19:09:04ZengElsevierInternational Journal of Infectious Diseases1201-97121878-35112015-03-0132C15616010.1016/j.ijid.2014.12.024Supporting clinical management of the difficult-to-treat TB cases: the ERS-WHO TB ConsiliumLia D’Ambrosio0Marina Tadolini1Rosella Centis2Raquel Duarte3Giovanni Sotgiu4Stefano Aliberti5Masoud Dara6Giovanni Battista Migliori7World Health Organization Collaborating Centre for Tuberculosis and Lung Diseases, Fondazione S. Maugeri, IRCCS, Via Roncaccio 16, 21049, Tradate, ItalySection of Infectious Diseases, Department of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, Via Massarenti 11, 40138, Bologna, ItalyWorld Health Organization Collaborating Centre for Tuberculosis and Lung Diseases, Fondazione S. Maugeri, IRCCS, Via Roncaccio 16, 21049, Tradate, ItalyPneumologia, Centro de Diagnóstico Pneumológico, Vila Nova de Gaia, Rua Conceição Fernandes 4430 PortugalClinical Epidemiology and Medical Statistics Unit, Department of Biomedical Sciences - University of Sassari – Research, Medical Education and Professional Development Unit, AOU Sassari, via Padre Manzella, 4, 07100, Sassari, ItalyHealth Science Department, University of Milan Bicocca, Respiratory Unit, AO San Gerardo, Via Pergolesi 33, 20052, Monza, ItalyWorld Health Organization, Regional Office for Europe, UN City Marmorvej 51 DK-2100 Copenhagen Ø, DenmarkWorld Health Organization Collaborating Centre for Tuberculosis and Lung Diseases, Fondazione S. Maugeri, IRCCS, Via Roncaccio 16, 21049, Tradate, ItalyMulti-drug and extensively drug-resistant tuberculosis (MDR/XDR-TB) are considered a serious threat for TB control and elimination. The outcome of these patients is still largely unsatisfactory as of today, with treatment success rates being consistently below 50% at global level. The World Health Organization (WHO) recommends that management of MDR-TB cases is supported by a specialized team, including complementary medical professionals able to cover several perspectives (clinical, both for adults and children; surgical; radiological; public health; psychological; nursing, among others). Implementation of such a body (known as Consilium in most of the former Soviet Union countries) is often a pre-requisite to apply for international TB control funding and concessionally priced medicines to treat M/XDR-TB cases. The primary objective of the ERS/WHO TB Consilium is to provide clinical consultation for drug-resistant TB and other difficult-to-treat TB cases, including co-infection with HIV and paediatric cases. Through technical guidance to clinicians managing complex TB cases, the main contribution and outcome of the initiative will be a public health response aimed at achieving correct treatment of affected patients and preventing further development of drug resistance. The Consilum's secondary objective is to ensure monitoring and evaluation of clinical practices on the ground (diagnosis, treatment and prevention).http://www.sciencedirect.com/science/article/pii/S1201971214017421MDR-TBXDR-TBclinical managementdrug resistancepreventionERS/WHO Consilium |
| spellingShingle | Lia D’Ambrosio Marina Tadolini Rosella Centis Raquel Duarte Giovanni Sotgiu Stefano Aliberti Masoud Dara Giovanni Battista Migliori Supporting clinical management of the difficult-to-treat TB cases: the ERS-WHO TB Consilium International Journal of Infectious Diseases MDR-TB XDR-TB clinical management drug resistance prevention ERS/WHO Consilium |
| title | Supporting clinical management of the difficult-to-treat TB cases: the ERS-WHO TB Consilium |
| title_full | Supporting clinical management of the difficult-to-treat TB cases: the ERS-WHO TB Consilium |
| title_fullStr | Supporting clinical management of the difficult-to-treat TB cases: the ERS-WHO TB Consilium |
| title_full_unstemmed | Supporting clinical management of the difficult-to-treat TB cases: the ERS-WHO TB Consilium |
| title_short | Supporting clinical management of the difficult-to-treat TB cases: the ERS-WHO TB Consilium |
| title_sort | supporting clinical management of the difficult to treat tb cases the ers who tb consilium |
| topic | MDR-TB XDR-TB clinical management drug resistance prevention ERS/WHO Consilium |
| url | http://www.sciencedirect.com/science/article/pii/S1201971214017421 |
| work_keys_str_mv | AT liadambrosio supportingclinicalmanagementofthedifficulttotreattbcasestheerswhotbconsilium AT marinatadolini supportingclinicalmanagementofthedifficulttotreattbcasestheerswhotbconsilium AT rosellacentis supportingclinicalmanagementofthedifficulttotreattbcasestheerswhotbconsilium AT raquelduarte supportingclinicalmanagementofthedifficulttotreattbcasestheerswhotbconsilium AT giovannisotgiu supportingclinicalmanagementofthedifficulttotreattbcasestheerswhotbconsilium AT stefanoaliberti supportingclinicalmanagementofthedifficulttotreattbcasestheerswhotbconsilium AT masouddara supportingclinicalmanagementofthedifficulttotreattbcasestheerswhotbconsilium AT giovannibattistamigliori supportingclinicalmanagementofthedifficulttotreattbcasestheerswhotbconsilium |