Pre-existing T-cell immunity to SARS-CoV-2 in unexposed healthy controls in Ecuador, as detected with a COVID-19 Interferon-Gamma Release Assay

Pre-existing T-cell immunity to SARS-CoV-2 in unexposed healthy controls in Ecuador, as detected with a COVID-19 Interferon-Gamma Release Assay

Background: Studies of T-cell immune responses against SARS-CoV-2 are important in understanding the immune status of individuals or populations. Here, we use a simple, cheap, and rapid whole blood stimulation assay - an Interferon-Gamma Release Assay (IGRA) - to study T-cell immunity to SARS-CoV-2...

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Bibliographic Details
Main Authors: Gustavo Echeverría, Ángel Guevara, Josefina Coloma, Alison Mera Ruiz, María Mercedes Vasquez, Eduardo Tejera, Jacobus H. de Waard
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:International Journal of Infectious Diseases
Subjects:
Pre-existing immunity
COVID-19
SARS-CoV-2
T cells
Interferon-Gamma (IFN-γ) release assay (IGRA)
ELISPOT
Online Access:http://www.sciencedirect.com/science/article/pii/S120197122100120X

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