Orai2 Modulates Store-Operated Ca<sup>2+</sup> Entry and Cell Cycle Progression in Breast Cancer Cells

Orai2 Modulates Store-Operated Ca<sup>2+</sup> Entry and Cell Cycle Progression in Breast Cancer Cells

Breast cancer is a heterogeneous disease from the histological and molecular expression point of view, and this heterogeneity determines cancer aggressiveness. Store-operated Ca<sup>2+</sup> entry (SOCE), a major mechanism for Ca<sup>2+</sup> entry in non-excitable cells, is...

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Bibliographic Details
Main Authors: Jose Sanchez-Collado, Jose J. Lopez, Carlos Cantonero, Isaac Jardin, Sergio Regodón, Pedro C. Redondo, Juan Gordillo, Tarik Smani, Gines M. Salido, Juan A. Rosado
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cancers
Subjects:
Orai2
breast cancer
store-operated calcium entry
NFAT
cell cycle
Online Access:https://www.mdpi.com/2072-6694/14/1/114

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