Variant alleles of the CYP1B1 gene are associated with colorectal cancer susceptibility

Variant alleles of the CYP1B1 gene are associated with colorectal cancer susceptibility

<p>Abstract</p> <p>Background</p> <p>CYP1B1 is a P450 enzyme which is involved in the activation of pro-carcinogens to carcinogens as well as sex hormone metabolism. Because differences in the activity of the enzyme have been correlated with variant alleles of single nu...

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Main Authors: Trubicka Joanna, Grabowska-Kłujszo Ewa, Suchy Janina, Masojć Bartłomiej, Serrano-Fernandez Pablo, Kurzawski Grzegorz, Cybulski Cezary, Górski Bohdan, Huzarski Tomasz, Byrski Tomasz, Gronwald Jacek, Złowocka Elżbieta, Kładny Józef, Banaszkiewicz Zbigniew, Wiśniowski Rafał, Kowalska Elżbieta, Lubinski Jan, Scott Rodney J
Format: Article
Language:English
Published: BMC 2010-08-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/10/420

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