Electron crystallography and dedicated electron-diffraction instrumentation
Electron diffraction (known also as ED, 3D ED or microED) is gaining momentum in science and industry. The application of electron diffraction in performing nano-crystallography on crystals smaller than 1 µm is a disruptive technology that is opening up fascinating new perspectives for a wide variet...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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International Union of Crystallography
2023-05-01
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| Series: | Acta Crystallographica Section E: Crystallographic Communications |
| Subjects: | |
| Online Access: | http://scripts.iucr.org/cgi-bin/paper?S2056989023003109 |
| _version_ | 1827824414421417984 |
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| author | Petra Simoncic Eva Romeijn Eric Hovestreydt Gunther Steinfeld Gustavo Santiso-Quiñones Johannes Merkelbach |
| author_facet | Petra Simoncic Eva Romeijn Eric Hovestreydt Gunther Steinfeld Gustavo Santiso-Quiñones Johannes Merkelbach |
| author_sort | Petra Simoncic |
| collection | DOAJ |
| description | Electron diffraction (known also as ED, 3D ED or microED) is gaining momentum in science and industry. The application of electron diffraction in performing nano-crystallography on crystals smaller than 1 µm is a disruptive technology that is opening up fascinating new perspectives for a wide variety of compounds required in the fields of chemical, pharmaceutical and advanced materials research. Electron diffraction enables the characterization of solid compounds complementary to neutron, powder X-ray and single-crystal X-ray diffraction, as it has the unique capability to measure nanometre-sized crystals. The recent introduction of dedicated instrumentation to perform ED experiments is a key aspect of the continued growth and success of this technology. In addition to the ultra-high-speed hybrid-pixel detectors enabling ED data collection in continuous rotation mode, a high-precision goniometer and horizontal layout have been determined as essential features of an electron diffractometer, both of which are embodied in the Eldico ED-1. Four examples of data collected on an Eldico ED-1 are showcased to demonstrate the potential and advantages of a dedicated electron diffractometer, covering selected applications and challenges of electron diffraction: (i) multiple reciprocal lattices, (ii) absolute structure of a chiral compound, and (iii) R-values achieved by kinematic refinement comparable to X-ray data. |
| first_indexed | 2024-03-12T02:26:07Z |
| format | Article |
| id | doaj.art-85fe54155669478eb97c30b31106e923 |
| institution | Directory Open Access Journal |
| issn | 2056-9890 |
| language | English |
| last_indexed | 2024-03-12T02:26:07Z |
| publishDate | 2023-05-01 |
| publisher | International Union of Crystallography |
| record_format | Article |
| series | Acta Crystallographica Section E: Crystallographic Communications |
| spelling | doaj.art-85fe54155669478eb97c30b31106e9232023-09-05T13:04:49ZengInternational Union of CrystallographyActa Crystallographica Section E: Crystallographic Communications2056-98902023-05-0179541042210.1107/S2056989023003109pk2676Electron crystallography and dedicated electron-diffraction instrumentationPetra Simoncic0Eva Romeijn1Eric Hovestreydt2Gunther Steinfeld3Gustavo Santiso-Quiñones4Johannes Merkelbach5Eldico Scientific AG, PARK INNOVAARE: delivery LAB, Villigen, Aargau5234, SwitzerlandEldico Scientific AG, PARK INNOVAARE: delivery LAB, Villigen, Aargau5234, SwitzerlandEldico Scientific AG, PARK INNOVAARE: delivery LAB, Villigen, Aargau5234, SwitzerlandEldico Scientific AG, PARK INNOVAARE: delivery LAB, Villigen, Aargau5234, SwitzerlandEldico Scientific AG, PARK INNOVAARE: delivery LAB, Villigen, Aargau5234, SwitzerlandEldico Scientific AG, PARK INNOVAARE: delivery LAB, Villigen, Aargau5234, SwitzerlandElectron diffraction (known also as ED, 3D ED or microED) is gaining momentum in science and industry. The application of electron diffraction in performing nano-crystallography on crystals smaller than 1 µm is a disruptive technology that is opening up fascinating new perspectives for a wide variety of compounds required in the fields of chemical, pharmaceutical and advanced materials research. Electron diffraction enables the characterization of solid compounds complementary to neutron, powder X-ray and single-crystal X-ray diffraction, as it has the unique capability to measure nanometre-sized crystals. The recent introduction of dedicated instrumentation to perform ED experiments is a key aspect of the continued growth and success of this technology. In addition to the ultra-high-speed hybrid-pixel detectors enabling ED data collection in continuous rotation mode, a high-precision goniometer and horizontal layout have been determined as essential features of an electron diffractometer, both of which are embodied in the Eldico ED-1. Four examples of data collected on an Eldico ED-1 are showcased to demonstrate the potential and advantages of a dedicated electron diffractometer, covering selected applications and challenges of electron diffraction: (i) multiple reciprocal lattices, (ii) absolute structure of a chiral compound, and (iii) R-values achieved by kinematic refinement comparable to X-ray data.http://scripts.iucr.org/cgi-bin/paper?S20569890230031093d electron diffractionnano crystallographyinstrumentationelectron diffractometer3d electron diffraction, nano crystallography, instrumentation, electron diffractometer |
| spellingShingle | Petra Simoncic Eva Romeijn Eric Hovestreydt Gunther Steinfeld Gustavo Santiso-Quiñones Johannes Merkelbach Electron crystallography and dedicated electron-diffraction instrumentation Acta Crystallographica Section E: Crystallographic Communications 3d electron diffraction nano crystallography instrumentation electron diffractometer 3d electron diffraction, nano crystallography, instrumentation, electron diffractometer |
| title | Electron crystallography and dedicated electron-diffraction instrumentation |
| title_full | Electron crystallography and dedicated electron-diffraction instrumentation |
| title_fullStr | Electron crystallography and dedicated electron-diffraction instrumentation |
| title_full_unstemmed | Electron crystallography and dedicated electron-diffraction instrumentation |
| title_short | Electron crystallography and dedicated electron-diffraction instrumentation |
| title_sort | electron crystallography and dedicated electron diffraction instrumentation |
| topic | 3d electron diffraction nano crystallography instrumentation electron diffractometer 3d electron diffraction, nano crystallography, instrumentation, electron diffractometer |
| url | http://scripts.iucr.org/cgi-bin/paper?S2056989023003109 |
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