Intracisternal ziconotide infusion. Clinical case of an inoperable pharynx cancer patient with severe cervico-facial pain syndrome
The authors describe the clinical case of a patient suffering from severe cervico-facial pain syndrome with great incident component from inoperable pharynx cancer. The patient that was poorly responding to systemic therapy with high doses of opioids, benefi ted from intrathecal administration of...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Publiediting
2015-03-01
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| Series: | Pathos |
| Subjects: | |
| Online Access: | http://www.pathos-journal.com/doc/2010_3_Casi_Mameli.pdf |
| _version_ | 1811283073235419136 |
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| author | Sergio Mameli Giovanni Maria Pisanu Angela Maria Pili Maura Carboni |
| author_facet | Sergio Mameli Giovanni Maria Pisanu Angela Maria Pili Maura Carboni |
| author_sort | Sergio Mameli |
| collection | DOAJ |
| description | The authors describe the clinical case of a patient suffering from
severe cervico-facial pain syndrome with great incident component from inoperable pharynx cancer. The patient that was poorly responding to systemic therapy with high doses of opioids,
benefi ted from intrathecal administration of ziconotide in combination with morphine and bupivacaine. After a long period of effectiveness (16 months), the patient complained of pain recurrence.The increase of ziconotide dose caused a serious adverse effect (psychosis), which led to the suspension of the drug. After four weeks washout, lower doses of the drug (1/4) administered at cervical segmental level; the patient achieved again a good pain relief. |
| first_indexed | 2024-04-13T02:04:04Z |
| format | Article |
| id | doaj.art-85ff5fd1cad64f6eae29fcc6a86cf5c7 |
| institution | Directory Open Access Journal |
| issn | 1593-2354 1593-2354 |
| language | English |
| last_indexed | 2024-04-13T02:04:04Z |
| publishDate | 2015-03-01 |
| publisher | Publiediting |
| record_format | Article |
| series | Pathos |
| spelling | doaj.art-85ff5fd1cad64f6eae29fcc6a86cf5c72022-12-22T03:07:31ZengPublieditingPathos1593-23541593-23542015-03-011733438Intracisternal ziconotide infusion. Clinical case of an inoperable pharynx cancer patient with severe cervico-facial pain syndromeSergio Mameli0Giovanni Maria Pisanu1Angela Maria Pili2Maura Carboni3Medicina del Dolore PO A. Businco, CagliariMedicina del Dolore PO A. Businco, CagliariMedicina del Dolore PO A. Businco, CagliariMedicina del Dolore PO A. Businco, CagliariThe authors describe the clinical case of a patient suffering from severe cervico-facial pain syndrome with great incident component from inoperable pharynx cancer. The patient that was poorly responding to systemic therapy with high doses of opioids, benefi ted from intrathecal administration of ziconotide in combination with morphine and bupivacaine. After a long period of effectiveness (16 months), the patient complained of pain recurrence.The increase of ziconotide dose caused a serious adverse effect (psychosis), which led to the suspension of the drug. After four weeks washout, lower doses of the drug (1/4) administered at cervical segmental level; the patient achieved again a good pain relief.http://www.pathos-journal.com/doc/2010_3_Casi_Mameli.pdfZiconotidepersistent chronic painhead-neck cancerintracisternal drug infusion |
| spellingShingle | Sergio Mameli Giovanni Maria Pisanu Angela Maria Pili Maura Carboni Intracisternal ziconotide infusion. Clinical case of an inoperable pharynx cancer patient with severe cervico-facial pain syndrome Pathos Ziconotide persistent chronic pain head-neck cancer intracisternal drug infusion |
| title | Intracisternal ziconotide infusion. Clinical case of an inoperable pharynx cancer patient with severe cervico-facial pain syndrome |
| title_full | Intracisternal ziconotide infusion. Clinical case of an inoperable pharynx cancer patient with severe cervico-facial pain syndrome |
| title_fullStr | Intracisternal ziconotide infusion. Clinical case of an inoperable pharynx cancer patient with severe cervico-facial pain syndrome |
| title_full_unstemmed | Intracisternal ziconotide infusion. Clinical case of an inoperable pharynx cancer patient with severe cervico-facial pain syndrome |
| title_short | Intracisternal ziconotide infusion. Clinical case of an inoperable pharynx cancer patient with severe cervico-facial pain syndrome |
| title_sort | intracisternal ziconotide infusion clinical case of an inoperable pharynx cancer patient with severe cervico facial pain syndrome |
| topic | Ziconotide persistent chronic pain head-neck cancer intracisternal drug infusion |
| url | http://www.pathos-journal.com/doc/2010_3_Casi_Mameli.pdf |
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