(<i>Z</i>)-2-(1-(5-Methyl-1-(4-nitrophenyl)-1<i>H</i>-1,2,3-triazol-4-yl)ethylidene)-<i>N</i>-phenylhydrazine-1-carbothioamide
Reaction of equimolar equivalents of 1-(5-methyl-1-(4-nitrophenyl)-1<i>H</i>-1,2,3-triazol-4-yl)ethan-1-one (<b>1</b>) and <i>N</i>-phenylhydrazinecarbothioamide (<b>2</b>) in boiling ethanol containing a catalytic amount of concentrated hydrochloric a...
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MDPI AG
2022-10-01
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| Online Access: | https://www.mdpi.com/1422-8599/2022/4/M1462 |
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| author | Benson M. Kariuki Bakr F. Abdel-Wahab Mohamed S. Bekheit Gamal A. El-Hiti |
| author_facet | Benson M. Kariuki Bakr F. Abdel-Wahab Mohamed S. Bekheit Gamal A. El-Hiti |
| author_sort | Benson M. Kariuki |
| collection | DOAJ |
| description | Reaction of equimolar equivalents of 1-(5-methyl-1-(4-nitrophenyl)-1<i>H</i>-1,2,3-triazol-4-yl)ethan-1-one (<b>1</b>) and <i>N</i>-phenylhydrazinecarbothioamide (<b>2</b>) in boiling ethanol containing a catalytic amount of concentrated hydrochloric acid for 4 h gave (<i>Z</i>)-2-(1-(5-methyl-1-(4-nitrophenyl)-1<i>H</i>-1,2,3-triazol-4-yl)ethylidene)-<i>N</i>-phenylhydrazine-1-carbothioamide (<b>3</b>) with 88% yield. The structure of <b>3</b> was established using single-crystal X-ray diffraction and magnetic resonance spectroscopy. |
| first_indexed | 2024-03-09T16:03:23Z |
| format | Article |
| id | doaj.art-8602f483b4d14e9b8efe76bfa8df270f |
| institution | Directory Open Access Journal |
| issn | 1422-8599 |
| language | English |
| last_indexed | 2024-03-09T16:03:23Z |
| publishDate | 2022-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molbank |
| spelling | doaj.art-8602f483b4d14e9b8efe76bfa8df270f2023-11-24T16:53:41ZengMDPI AGMolbank1422-85992022-10-0120224M146210.3390/M1462(<i>Z</i>)-2-(1-(5-Methyl-1-(4-nitrophenyl)-1<i>H</i>-1,2,3-triazol-4-yl)ethylidene)-<i>N</i>-phenylhydrazine-1-carbothioamideBenson M. Kariuki0Bakr F. Abdel-Wahab1Mohamed S. Bekheit2Gamal A. El-Hiti3School of Chemistry, Cardiff University, Main Building, Park Place, Cardiff CF10 3AT, UKApplied Organic Chemistry Department, Chemical Industries Research Institute, National Research Centre, Dokki, Giza 12622, EgyptDepartment of Pesticide Chemistry, National Research Centre, Dokki, Giza 12622, EgyptCornea Research Chair, Department of Optometry, College of Applied Medical Sciences, King Saud University, Riyadh 11433, Saudi ArabiaReaction of equimolar equivalents of 1-(5-methyl-1-(4-nitrophenyl)-1<i>H</i>-1,2,3-triazol-4-yl)ethan-1-one (<b>1</b>) and <i>N</i>-phenylhydrazinecarbothioamide (<b>2</b>) in boiling ethanol containing a catalytic amount of concentrated hydrochloric acid for 4 h gave (<i>Z</i>)-2-(1-(5-methyl-1-(4-nitrophenyl)-1<i>H</i>-1,2,3-triazol-4-yl)ethylidene)-<i>N</i>-phenylhydrazine-1-carbothioamide (<b>3</b>) with 88% yield. The structure of <b>3</b> was established using single-crystal X-ray diffraction and magnetic resonance spectroscopy.https://www.mdpi.com/1422-8599/2022/4/M1462synthesis1,2,3-triazole<i>N</i>-phenylhydrazinecarbothioamideX-ray diffractionheterocycleshydrazones |
| spellingShingle | Benson M. Kariuki Bakr F. Abdel-Wahab Mohamed S. Bekheit Gamal A. El-Hiti (<i>Z</i>)-2-(1-(5-Methyl-1-(4-nitrophenyl)-1<i>H</i>-1,2,3-triazol-4-yl)ethylidene)-<i>N</i>-phenylhydrazine-1-carbothioamide Molbank synthesis 1,2,3-triazole <i>N</i>-phenylhydrazinecarbothioamide X-ray diffraction heterocycles hydrazones |
| title | (<i>Z</i>)-2-(1-(5-Methyl-1-(4-nitrophenyl)-1<i>H</i>-1,2,3-triazol-4-yl)ethylidene)-<i>N</i>-phenylhydrazine-1-carbothioamide |
| title_full | (<i>Z</i>)-2-(1-(5-Methyl-1-(4-nitrophenyl)-1<i>H</i>-1,2,3-triazol-4-yl)ethylidene)-<i>N</i>-phenylhydrazine-1-carbothioamide |
| title_fullStr | (<i>Z</i>)-2-(1-(5-Methyl-1-(4-nitrophenyl)-1<i>H</i>-1,2,3-triazol-4-yl)ethylidene)-<i>N</i>-phenylhydrazine-1-carbothioamide |
| title_full_unstemmed | (<i>Z</i>)-2-(1-(5-Methyl-1-(4-nitrophenyl)-1<i>H</i>-1,2,3-triazol-4-yl)ethylidene)-<i>N</i>-phenylhydrazine-1-carbothioamide |
| title_short | (<i>Z</i>)-2-(1-(5-Methyl-1-(4-nitrophenyl)-1<i>H</i>-1,2,3-triazol-4-yl)ethylidene)-<i>N</i>-phenylhydrazine-1-carbothioamide |
| title_sort | i z i 2 1 5 methyl 1 4 nitrophenyl 1 i h i 1 2 3 triazol 4 yl ethylidene i n i phenylhydrazine 1 carbothioamide |
| topic | synthesis 1,2,3-triazole <i>N</i>-phenylhydrazinecarbothioamide X-ray diffraction heterocycles hydrazones |
| url | https://www.mdpi.com/1422-8599/2022/4/M1462 |
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