Efficacy of low‐fat milk and yogurt fortified with encapsulated vitamin D3 on improvement in symptoms of insomnia and quality of life: Evidence from the SUVINA trial
Abstract Introduction Sleep disorders are a common condition globally. Vitamin D receptors are present on cells in several regions of the brain. It is possible that vitamin D status may affect brain function, including sleep patterns. We aimed to evaluate the 1,500 IU of Nano‐encapsulated vitamin D...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2020-08-01
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| Series: | Food Science & Nutrition |
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| Online Access: | https://doi.org/10.1002/fsn3.1750 |
| _version_ | 1797661195102060544 |
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| author | Payam Sharifan Mahdieh Khoshakhlagh Zahra Khorasanchi Susan Darroudi Mitra Rezaie Mohammad Safarian Hassan Vatanparast Asma Afshari Gordon Ferns Hamideh Ghazizadeh Majid Ghayour Mobarhan |
| author_facet | Payam Sharifan Mahdieh Khoshakhlagh Zahra Khorasanchi Susan Darroudi Mitra Rezaie Mohammad Safarian Hassan Vatanparast Asma Afshari Gordon Ferns Hamideh Ghazizadeh Majid Ghayour Mobarhan |
| author_sort | Payam Sharifan |
| collection | DOAJ |
| description | Abstract Introduction Sleep disorders are a common condition globally. Vitamin D receptors are present on cells in several regions of the brain. It is possible that vitamin D status may affect brain function, including sleep patterns. We aimed to evaluate the 1,500 IU of Nano‐encapsulated vitamin D fortified in dairy products on the symptoms of insomnia and associated improvement of quality of life. Methods A case series was undertaken as part of the Survey of ultraviolent intake by nutritional approach project. Subjects enrolled among adults with abdominal obesity. Twenty‐nine subjects with insomnia were selected according to the results of Insomnia Severity Index questionnaire and quality of life using a Short Form Health Survey (SF‐36) questionnaire. Subjects were allocated to four groups: low‐fat milk fortified by 1,500 IU vitamin D3 (n = 8), simple milk (n = 8), low‐fat yogurt fortified by 1,500 IU vitamin D3 (n = 7), and simple yogurt (n = 6) and were treated for 10 weeks. Results The insomnia score improved after the intervention in the group receiving vitamin D fortified milk compared to group receiving unfortified milk (p < .001). There were no significant differences between the two groups taking yogurt (fortified vs. unfortified). Comparison of quality of life scores between baseline and after intervention indicated significant improvements in both fortified and simple milk groups (p = .002 and p = .03, respectively); but no differences were found in the groups taking yogurt. Conclusion Fortified low‐fat milk containing 1,500 IU vitamin D3 can improve insomnia symptoms and subsequently quality of life. Trial registration number: IRCT20101130005280N27, www.IRCT.ir. |
| first_indexed | 2024-03-11T18:41:48Z |
| format | Article |
| id | doaj.art-8604350a75ee42baaff3a0347519a471 |
| institution | Directory Open Access Journal |
| issn | 2048-7177 |
| language | English |
| last_indexed | 2024-03-11T18:41:48Z |
| publishDate | 2020-08-01 |
| publisher | Wiley |
| record_format | Article |
| series | Food Science & Nutrition |
| spelling | doaj.art-8604350a75ee42baaff3a0347519a4712023-10-12T12:06:11ZengWileyFood Science & Nutrition2048-71772020-08-01884484449010.1002/fsn3.1750Efficacy of low‐fat milk and yogurt fortified with encapsulated vitamin D3 on improvement in symptoms of insomnia and quality of life: Evidence from the SUVINA trialPayam Sharifan0Mahdieh Khoshakhlagh1Zahra Khorasanchi2Susan Darroudi3Mitra Rezaie4Mohammad Safarian5Hassan Vatanparast6Asma Afshari7Gordon Ferns8Hamideh Ghazizadeh9Majid Ghayour Mobarhan10Department of Nutrition School of Medicine Mashhad University of Medical Sciences Mashhad IranDepartment of Medical Biochemistry Faculty of Medicine Mashhad University of Medical Sciences Mashhad IranDepartment of Nutrition School of Medicine Mashhad University of Medical Sciences Mashhad IranMetabolic Syndrome Research Center Mashhad University of Medical Sciences Mashhad IranDepartment of Nutrition School of Medicine Mashhad University of Medical Sciences Mashhad IranDepartment of Nutrition School of Medicine Mashhad University of Medical Sciences Mashhad IranCollege of Pharmacy and Nutrition University of Saskatchewan Saskatoon SK CanadaDepartment of Nutrition School of Medicine Mashhad University of Medical Sciences Mashhad IranBrighton and Sussex Medical School Division of Medical Education Brighton UKMetabolic Syndrome Research Center Mashhad University of Medical Sciences Mashhad IranDepartment of Nutrition School of Medicine Mashhad University of Medical Sciences Mashhad IranAbstract Introduction Sleep disorders are a common condition globally. Vitamin D receptors are present on cells in several regions of the brain. It is possible that vitamin D status may affect brain function, including sleep patterns. We aimed to evaluate the 1,500 IU of Nano‐encapsulated vitamin D fortified in dairy products on the symptoms of insomnia and associated improvement of quality of life. Methods A case series was undertaken as part of the Survey of ultraviolent intake by nutritional approach project. Subjects enrolled among adults with abdominal obesity. Twenty‐nine subjects with insomnia were selected according to the results of Insomnia Severity Index questionnaire and quality of life using a Short Form Health Survey (SF‐36) questionnaire. Subjects were allocated to four groups: low‐fat milk fortified by 1,500 IU vitamin D3 (n = 8), simple milk (n = 8), low‐fat yogurt fortified by 1,500 IU vitamin D3 (n = 7), and simple yogurt (n = 6) and were treated for 10 weeks. Results The insomnia score improved after the intervention in the group receiving vitamin D fortified milk compared to group receiving unfortified milk (p < .001). There were no significant differences between the two groups taking yogurt (fortified vs. unfortified). Comparison of quality of life scores between baseline and after intervention indicated significant improvements in both fortified and simple milk groups (p = .002 and p = .03, respectively); but no differences were found in the groups taking yogurt. Conclusion Fortified low‐fat milk containing 1,500 IU vitamin D3 can improve insomnia symptoms and subsequently quality of life. Trial registration number: IRCT20101130005280N27, www.IRCT.ir.https://doi.org/10.1002/fsn3.1750fortificationinsomniasleep disordersvitamin D3 |
| spellingShingle | Payam Sharifan Mahdieh Khoshakhlagh Zahra Khorasanchi Susan Darroudi Mitra Rezaie Mohammad Safarian Hassan Vatanparast Asma Afshari Gordon Ferns Hamideh Ghazizadeh Majid Ghayour Mobarhan Efficacy of low‐fat milk and yogurt fortified with encapsulated vitamin D3 on improvement in symptoms of insomnia and quality of life: Evidence from the SUVINA trial Food Science & Nutrition fortification insomnia sleep disorders vitamin D3 |
| title | Efficacy of low‐fat milk and yogurt fortified with encapsulated vitamin D3 on improvement in symptoms of insomnia and quality of life: Evidence from the SUVINA trial |
| title_full | Efficacy of low‐fat milk and yogurt fortified with encapsulated vitamin D3 on improvement in symptoms of insomnia and quality of life: Evidence from the SUVINA trial |
| title_fullStr | Efficacy of low‐fat milk and yogurt fortified with encapsulated vitamin D3 on improvement in symptoms of insomnia and quality of life: Evidence from the SUVINA trial |
| title_full_unstemmed | Efficacy of low‐fat milk and yogurt fortified with encapsulated vitamin D3 on improvement in symptoms of insomnia and quality of life: Evidence from the SUVINA trial |
| title_short | Efficacy of low‐fat milk and yogurt fortified with encapsulated vitamin D3 on improvement in symptoms of insomnia and quality of life: Evidence from the SUVINA trial |
| title_sort | efficacy of low fat milk and yogurt fortified with encapsulated vitamin d3 on improvement in symptoms of insomnia and quality of life evidence from the suvina trial |
| topic | fortification insomnia sleep disorders vitamin D3 |
| url | https://doi.org/10.1002/fsn3.1750 |
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