Muscle stem cells and fibro-adipogenic progenitors in female pelvic floor muscle regeneration following birth injury

Muscle stem cells and fibro-adipogenic progenitors in female pelvic floor muscle regeneration following birth injury

Abstract Pelvic floor muscle (PFM) injury during childbirth is a key risk factor for pelvic floor disorders that affect millions of women worldwide. Muscle stem cells (MuSCs), supported by the fibro-adipogenic progenitors (FAPs) and immune cells, are indispensable for the regeneration of injured app...

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Bibliographic Details
Main Authors: Francesca Boscolo Sesillo, Varsha Rajesh, Michelle Wong, Pamela Duran, John B. Rudell, Courtney P. Rundio, Brittni B. Baynes, Louise C. Laurent, Alessandra Sacco, Karen L. Christman, Marianna Alperin
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:npj Regenerative Medicine
Online Access:https://doi.org/10.1038/s41536-022-00264-1

Internet

https://doi.org/10.1038/s41536-022-00264-1

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