Clinical evaluation of Major Depressive Disorder (MDD) and Borderline Personality Disorder(BPD) in youth adolescents

Introduction According to international studies, at least 70% of BPD in adolescence are comorbid with MDD. Objectives To determine the clinical and psychopathological markers of MDD in BPD in adolescence. Methods Clinical psychopathological interview, SCID-II, Hamilton Depression Rating Scale (HD...

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Main Authors: V. Kaleda, E. Krylova, A. Kuleshov, A. Beburishvili
Format: Article
Language:English
Published: Cambridge University Press 2022-06-01
Series:European Psychiatry
Subjects:
Online Access:https://www.cambridge.org/core/product/identifier/S0924933822008343/type/journal_article
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author V. Kaleda
E. Krylova
A. Kuleshov
A. Beburishvili
author_facet V. Kaleda
E. Krylova
A. Kuleshov
A. Beburishvili
author_sort V. Kaleda
collection DOAJ
description Introduction According to international studies, at least 70% of BPD in adolescence are comorbid with MDD. Objectives To determine the clinical and psychopathological markers of MDD in BPD in adolescence. Methods Clinical psychopathological interview, SCID-II, Hamilton Depression Rating Scale (HDRS). Sample: N=73 male and female, age: 18-25 with MDD and BPD. Results MDD comorbid with BPD in adolescence is characterized by polymorphism of its’ psychopathological manifestations due to the structure of BPD and the input of the age factor. In the studied sample 31 (42,5%) with both MDD and BPD also revealed addictions; 24 patients (32,9%) - anxiety and obsessive-compulsive (OCD) disorders, 18 patients (24,7%) had overvalued ideas. The high contingency of MDD with autoaggressive actions confirmed their high suicidal risk (53 patients). Among them - 31 patients (58,5%) - had non-suicidal self-harm (NSSI), 7 patients – (13,2%) had suicidal attempt (SA), and 15 patients (28,3%) had NSSI and suicidal attempts (NSSI+SA). The highest incidence of NSSI and NSSI+SA was noted in MDD with addictive disorders: NSSI – N=20 (80,00%), NSSI+SA - N=5 (20,00%), SA – N=0. MDD with BPD and anxiety disorders: NSSI – N=9 (56,25%), NSSI+SA – N= 6 (37,50%), SA–N=1 (6,25%). MDD with BPD and overvalued ideas: NSSI – N=2 (16,67%), NSSI +SA – N= 4 (33,33%), SA N=6 (50,0%), (results p<0.01). Conclusions Psychopathological relations between BPD and MDD in youth are different due to additional comorbid conditions, like addictions, anxiety and OCD, overvalued ideas and have clinical implications in terms of suicidal and NSSI risks, individualized interventions and prognosis. Disclosure No significant relationships.
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spelling doaj.art-8615bbc943774d27acb5584b02c0f7fe2023-11-17T05:06:15ZengCambridge University PressEuropean Psychiatry0924-93381778-35852022-06-0165S328S32810.1192/j.eurpsy.2022.834Clinical evaluation of Major Depressive Disorder (MDD) and Borderline Personality Disorder(BPD) in youth adolescentsV. Kaleda0E. Krylova1A. Kuleshov2A. Beburishvili3FSBSI «Mental Health Research Centre», Department Of Youth Psychiatry, Moscow, Russian FederationFSBSI «Mental Health Research Centre», Department Of Youth Psychiatry, Moscow, Russian FederationFSBSI «Mental Health Research Centre», Department Of Youth Psychiatry, Moscow, Russian FederationFSBSI «Mental Health Research Centre», Department Of Youth Psychiatry, Moscow, Russian Federation Introduction According to international studies, at least 70% of BPD in adolescence are comorbid with MDD. Objectives To determine the clinical and psychopathological markers of MDD in BPD in adolescence. Methods Clinical psychopathological interview, SCID-II, Hamilton Depression Rating Scale (HDRS). Sample: N=73 male and female, age: 18-25 with MDD and BPD. Results MDD comorbid with BPD in adolescence is characterized by polymorphism of its’ psychopathological manifestations due to the structure of BPD and the input of the age factor. In the studied sample 31 (42,5%) with both MDD and BPD also revealed addictions; 24 patients (32,9%) - anxiety and obsessive-compulsive (OCD) disorders, 18 patients (24,7%) had overvalued ideas. The high contingency of MDD with autoaggressive actions confirmed their high suicidal risk (53 patients). Among them - 31 patients (58,5%) - had non-suicidal self-harm (NSSI), 7 patients – (13,2%) had suicidal attempt (SA), and 15 patients (28,3%) had NSSI and suicidal attempts (NSSI+SA). The highest incidence of NSSI and NSSI+SA was noted in MDD with addictive disorders: NSSI – N=20 (80,00%), NSSI+SA - N=5 (20,00%), SA – N=0. MDD with BPD and anxiety disorders: NSSI – N=9 (56,25%), NSSI+SA – N= 6 (37,50%), SA–N=1 (6,25%). MDD with BPD and overvalued ideas: NSSI – N=2 (16,67%), NSSI +SA – N= 4 (33,33%), SA N=6 (50,0%), (results p<0.01). Conclusions Psychopathological relations between BPD and MDD in youth are different due to additional comorbid conditions, like addictions, anxiety and OCD, overvalued ideas and have clinical implications in terms of suicidal and NSSI risks, individualized interventions and prognosis. Disclosure No significant relationships. https://www.cambridge.org/core/product/identifier/S0924933822008343/type/journal_articlemajor depressive disordernonsuicidal self-injury suicidal behaviourborderline personality disorder
spellingShingle V. Kaleda
E. Krylova
A. Kuleshov
A. Beburishvili
Clinical evaluation of Major Depressive Disorder (MDD) and Borderline Personality Disorder(BPD) in youth adolescents
European Psychiatry
major depressive disorder
nonsuicidal self-injury
suicidal behaviour
borderline personality disorder
title Clinical evaluation of Major Depressive Disorder (MDD) and Borderline Personality Disorder(BPD) in youth adolescents
title_full Clinical evaluation of Major Depressive Disorder (MDD) and Borderline Personality Disorder(BPD) in youth adolescents
title_fullStr Clinical evaluation of Major Depressive Disorder (MDD) and Borderline Personality Disorder(BPD) in youth adolescents
title_full_unstemmed Clinical evaluation of Major Depressive Disorder (MDD) and Borderline Personality Disorder(BPD) in youth adolescents
title_short Clinical evaluation of Major Depressive Disorder (MDD) and Borderline Personality Disorder(BPD) in youth adolescents
title_sort clinical evaluation of major depressive disorder mdd and borderline personality disorder bpd in youth adolescents
topic major depressive disorder
nonsuicidal self-injury
suicidal behaviour
borderline personality disorder
url https://www.cambridge.org/core/product/identifier/S0924933822008343/type/journal_article
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