ANALGESIC NEPHROPATHY. A MODERN VIEW ON THE PROBLEM

Aim. To review Russian and foreign literature on modern methods of diagnosis and treatment of patients with analgesic nephropathy.Materials and methods. Russian and foreign literature sources published in recent years on the aforementioned problem were analyzed.Results. This article presents the con...

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Main Author: Olga B. Poselugina
Format: Article
Language:Russian
Published: Ministry of Healthcare of the Russian Federation. “Kuban State Medical University” 2019-05-01
Series:Кубанский научный медицинский вестник
Subjects:
Online Access:https://ksma.elpub.ru/jour/article/view/1718
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author Olga B. Poselugina
author_facet Olga B. Poselugina
author_sort Olga B. Poselugina
collection DOAJ
description Aim. To review Russian and foreign literature on modern methods of diagnosis and treatment of patients with analgesic nephropathy.Materials and methods. Russian and foreign literature sources published in recent years on the aforementioned problem were analyzed.Results. This article presents the concept of analgesic nephropathy (AN) and discusses causes and mechanisms of its development. The pathogenic effect of non-steroidal antiinfl ammatory drugs on renal tissue is indicated. Key stages of the disease and its clinical features are determined. An algorithm of diagnosis is proposed. The importance of a patient’s detailed medical history is emphasized, including the duration, multiplicity and reasons for taking analgesics. A particular attention is paid to questions of AN therapy and its prevention. Provided timely diagnosis and analgesics withdrawal, the possibility of reverting tubulointerstitial infl ammation is shown.Conclusion. It is shown that optimal solutions with regard to AN diagnosis and its treatment are yet to be found. A timely diagnosis inhibits the development of chronic renal failure, which early detection provides for a higher treatment effi ciency and improved prognosis.
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spelling doaj.art-861a218b446145328d9063105e317d092024-02-25T10:57:23ZrusMinistry of Healthcare of the Russian Federation. “Kuban State Medical University”Кубанский научный медицинский вестник1608-62282541-95442019-05-0126219120110.25207/1608-6228-2019-26-2-191-2011099ANALGESIC NEPHROPATHY. A MODERN VIEW ON THE PROBLEMOlga B. Poselugina0Tver State Medical University, Ministry of Healthcare of the Russian FederationAim. To review Russian and foreign literature on modern methods of diagnosis and treatment of patients with analgesic nephropathy.Materials and methods. Russian and foreign literature sources published in recent years on the aforementioned problem were analyzed.Results. This article presents the concept of analgesic nephropathy (AN) and discusses causes and mechanisms of its development. The pathogenic effect of non-steroidal antiinfl ammatory drugs on renal tissue is indicated. Key stages of the disease and its clinical features are determined. An algorithm of diagnosis is proposed. The importance of a patient’s detailed medical history is emphasized, including the duration, multiplicity and reasons for taking analgesics. A particular attention is paid to questions of AN therapy and its prevention. Provided timely diagnosis and analgesics withdrawal, the possibility of reverting tubulointerstitial infl ammation is shown.Conclusion. It is shown that optimal solutions with regard to AN diagnosis and its treatment are yet to be found. A timely diagnosis inhibits the development of chronic renal failure, which early detection provides for a higher treatment effi ciency and improved prognosis.https://ksma.elpub.ru/jour/article/view/1718tubulointerstitial nephritisanalgesicsrenal failure
spellingShingle Olga B. Poselugina
ANALGESIC NEPHROPATHY. A MODERN VIEW ON THE PROBLEM
Кубанский научный медицинский вестник
tubulointerstitial nephritis
analgesics
renal failure
title ANALGESIC NEPHROPATHY. A MODERN VIEW ON THE PROBLEM
title_full ANALGESIC NEPHROPATHY. A MODERN VIEW ON THE PROBLEM
title_fullStr ANALGESIC NEPHROPATHY. A MODERN VIEW ON THE PROBLEM
title_full_unstemmed ANALGESIC NEPHROPATHY. A MODERN VIEW ON THE PROBLEM
title_short ANALGESIC NEPHROPATHY. A MODERN VIEW ON THE PROBLEM
title_sort analgesic nephropathy a modern view on the problem
topic tubulointerstitial nephritis
analgesics
renal failure
url https://ksma.elpub.ru/jour/article/view/1718
work_keys_str_mv AT olgabposelugina analgesicnephropathyamodernviewontheproblem